Ornithine
Ornithine, arginine, and citrulline are the three amino acids involved in the urea cycle. Your body uses ornithine to make polyamines (which play a role in cell growth and proliferation) and the amino acid proline (used to make collagen). Preliminary evidence suggests that ornithine supplementation can improve athletic performance by reducing elevated levels of ammonia.
Quick Answer
What it is
Ornithine, arginine, and citrulline are the three amino acids involved in the urea cycle. Your body uses ornithine to make polyamines (which play a role in cell growth and proliferation) and the amino acid proline (used to make collagen).
Key findings
- Grade C: Ammonia (Fatigue)
- Grade C: Cortisol (Metabolic Health)
- Grade D: Blood Pressure (Fatigue)
Safety
No specific caution or interaction language was detected in the current summary/outcome notes.
ℹ️ Quick Facts: Ornithine
Quick Facts: Ornithine
- Best Evidence:Grade C
- Conditions Studied:3
- Research Outcomes:16
- Key Effect:Fatigue
Detailed Outcomes
Evidence by Condition
Best grade per condition (each condition may have multiple outcomes)
Research Citations (3)
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