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Fecal Transplant

A fecal transplant moves gut bacteria from a healthy donor's stool into another person's intestines, reshaping the microbes that help digest food. People mostly look at it for irritable bowel syndrome, and the evidence is limited: in a small group of 164 people, bloating improved. Abdominal pain showed no clear difference, and the evidence there is very limited, so the picture is still early.

Updated 30 September 2026
How we grade
1 study cited

Best evidence: Grade C
Conditions studied: 3
Outcomes: 12
Graded outcomes: 0012

Evidence by condition

Strong
Moderate
Limited
Very limited

3 conditions

Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome (IBS): outcomes studied for Fecal Transplant
Grade	Outcome	Effect	Size	Studies	People
	Bloating Small Improvement	Improves (the measure goes down)	Small effect		164 people
	Abdominal Pain No effect		NoneNo effect		8,315 people
	Irritable Bowel Syndrome Symptoms	Improves (the measure goes down)		1 study	8,315 people
Studies that measured irritable bowel syndrome symptoms The Efficacy of Probiotics, Prebiotics, Synbiotics, and Fecal Microbiota Transplantation in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis.Nutrients · PMID 38999862

Nonalcoholic Fatty Liver Disease (NAFLD)

Nonalcoholic Fatty Liver Disease (NAFLD): outcomes studied for Fecal Transplant
Grade	Outcome	Effect	Size	Studies	People
	Body Mass Index (BMI) No effect		NoneNo effect		1,921 people
	Insulin Resistance	Improves (the measure goes down)		1 study	1,921 people
Studies that measured insulin resistance The effect of gut microbiome-targeted therapies in nonalcoholic fatty liver disease: a systematic review and network meta-analysis.Front Nutr · PMID 39834471
	High-density lipoprotein (HDL)	Improves (the measure goes up)			1,921 people
	Liver Enzymes	Changes; see studies			1,921 people
	Liver Fibrosis	Improves (the measure goes down)			1,921 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			1,921 people
	Total cholesterol	Improves (the measure goes down)			1,921 people
	Triglycerides	Improves (the measure goes down)			1,921 people

Inflammatory Bowel Disease (IBD)

Inflammatory Bowel Disease (IBD): outcomes studied for Fecal Transplant
Grade	Outcome	Effect	Size	Studies	People	Studies list
	Inflammatory Bowel Disease Symptoms	Improves (the measure goes down)		1 study	1 person
Studies that measured inflammatory bowel disease symptoms Effectiveness and safety of non-pharmacological therapies for the treatment of inflammatory bowel disease: a network meta-analysis.Front Med · PMID 40662074

Key findings

BloatingIrritable Bowel Syndrome (IBS)Improves (the measure goes down)
Abdominal PainIrritable Bowel Syndrome (IBS)
Body Mass Index (BMI)Nonalcoholic Fatty Liver Disease (NAFLD)

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Grade C

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Studies cited

1 study from PubMed

Effectiveness and safety of non-pharmacological therapies for the treatment of inflammatory bowel disease: a network meta-analysis.Front Med · PMID 40662074