Synbiotics

Synbiotics refer to combinations of probiotics and prebiotics that may have a synergetic effect on the gut microbiome. Synbiotics are often used as dietary supplements or food ingredients.

Quick Answer

What it is

Synbiotics refer to combinations of probiotics and prebiotics that may have a synergetic effect on the gut microbiome. Synbiotics are often used as dietary supplements or food ingredients.

Key findings

  • Grade B: Blood Pressure (Nonalcoholic Fatty Liver Disease (NAFLD))
  • Grade D: Body Fat (Nonalcoholic Fatty Liver Disease (NAFLD))
  • Grade D: Height (Malnutrition)

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

โ„น๏ธ Quick Facts: Synbiotics

Quick Facts: Synbiotics

  • Best Evidence:Grade B
  • Conditions Studied:5
  • Research Outcomes:33
  • Grade B Findings:2
  • Key Effect:Nonalcoholic Fatty Liver Disease (NAFLD)
Outcomes by grade:
A0
B2
C0
D3
5 conditions ยท 33 outcomes

Detailed Outcomes

|
B
Blood Pressure
Mixed effect
4 studies
D
Body Fat
No effect
3 studies
none
?
Liver Enzymes
โ†‘Worsens
?
Total cholesterol
12 studies
โ†“Improves
?
Triglycerides
12 studies
โ†“Improves
?
High-density lipoprotein (HDL)
10 studies
โ†‘Improves
?
Low-density lipoprotein (LDL)
10 studies
โ†“Improves
?
Weight
โ†“Improves
?
C-Reactive Protein (CRP)
7 studies
โ†“Improves
?
TNF-Alpha
5 studies
โ†“Improves
?
Waist circumference
5 studies
โ†“Improves
?
Liver Fibrosis
4 studies
โ†“Improves
?
Liver Fat
3 studies
โ†“Improves
?
Body Mass Index (BMI)
1 study
โ†“Improves
?
Insulin Resistance
1 study
โ†“Improves
B
Blood Pressure
Mixed effect
4 studies
?
Liver Enzymes
โ†‘Worsens
?
Total cholesterol
12 studies
โ†“Improves
?
Weight
โ†“Improves
?
C-Reactive Protein (CRP)
7 studies
โ†“Improves
?
TNF-Alpha
5 studies
โ†“Improves
?
Waist circumference
5 studies
โ†“Improves
?
Liver Fibrosis
4 studies
โ†“Improves
?
Body Fat
3 studies
โ†“Improves
?
Liver Fat
3 studies
โ†“Improves
D
Height
No effect
2 studies
none
?
Weight
โ†“Improves
?
Lower Respiratory Tract Infection Risk
1 study
โ†‘Worsens
D
Abdominal Pain
No effect
1 study
none
?
Bloating
1 study
โ†“Improves
?
Irritable Bowel Syndrome Symptoms
1 study
โ†“Improves
?
Quality of Life
1 study
โ†‘Improves
?
Lung Function
2 studies
โ†‘Improves

Related Supplements

Probiotics

4 shared conditions ยท 215 outcomes

Probiotics are microorganisms that can have a positive effect on health.

Vitamin E

3 shared conditions ยท 274 outcomes

Vitamin E is a fat-soluble antioxidant that protects cells from oxidative damage and is found in several common foods. Supplementing with extra vitamin E does not have broad health benefits, except in people with vitamin E deficiency, and long-term high-dose supplementation may cause harm.

Vitamin D

3 shared conditions ยท 308 outcomes

Vitamin D is a fat-soluble vitamin that our skin synthesizes when exposed to the sun. It benefits us in many ways, from bone health to mood.

Prebiotics

3 shared conditions ยท 13 outcomes

Prebiotics are nutrients found in food that increase the amount of bacteria in the gastrointestinal system. Fiber from fruits and vegetables are abundant in many types of prebiotics.

Silymarin

2 shared conditions ยท 13 outcomes

Silymarin is a complex mixture of plant-derived compounds extracted from milk thistle. It mostly contains flavonolignans and flavonoids, which have antioxidant and anti-inflammatory properties.

Melatonin

2 shared conditions ยท 141 outcomes

Melatonin is a hormone secreted in the brain that regulates sleep. It appears to be highly sensitive to light therapy and dark therapy. Oral ingestion of melatonin may be used as a sleep aid. It is non-addictive.

Fish Oil

2 shared conditions ยท 448 outcomes

Fish oil is a mix of mostly EPA and DHA derived from fatty fish. It reduces triglycerides, but does not seem to affect the rate of cardiovascular events. It appears to reduce the symptoms of depression and improve some painful, inflammatory conditions.

Fecal Transplant

2 shared conditions ยท 12 outcomes

A fecal transplant is a procedure in which stool is collected from a healthy donor and introduced into the gastrointestinal tract of a recipient to increase their healthy bacteria count. Fecal transplants are often used to control Clostridium difficile (C. diff) infection.