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Supplement

Betalains

Betalains are the red-violet and yellow pigments in beetroot and a few other plants, and they act as antioxidants in the body. In small trials, runners finished 5-10km efforts about 2-3% faster with a lower heart rate and perceived effort, and muscle damage markers returned to baseline within a day after exercise. The evidence is limited, though, and the blood pressure benefits of beetroot seem to come from its nitrate rather than betalains.

Best evidence
Grade C
Conditions studied
4
Outcomes
4
Graded outcomes
0031

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

4 conditions

Running Performance: outcomes studied for Betalains
GradeOutcomeEffectSizeStudiesPeopleStudies list
5-10km Time Trial

50-100mg BRC for 6-7 days improved 5-10km time by 2-3%; lower HR, RPE, and blood lactate (PMID: 29910288)

Improves (the measure goes up)Small effect35 people
Cycling Performance: outcomes studied for Betalains
GradeOutcomeEffectSizeStudiesPeopleStudies list
Power Output

7-day BLN (100mg/day) improved average absolute power vs placebo without increasing plasma NOx (PMID: 30155761)

Improves (the measure goes up)Small effect28 people

Muscle Recovery

  • Exercise Recovery Markers: improves
Muscle Recovery: outcomes studied for Betalains
GradeOutcomeEffectSizeStudiesPeopleStudies list
Exercise Recovery Markers

CK and LDH returned to baseline 24h post-exercise only with BRC; beetroot juice attenuated muscle damage (PMID: 26537365)

Improves (the measure goes up)Small effect43 people
High Blood Pressure: outcomes studied for Betalains
GradeOutcomeEffectSizeStudiesPeopleStudies list
Systolic BP

Betalains alone do not appear responsible for beetroot BP effects - nitrate is the active component

NoneNo effect50 people

Key findings

  • 5-10km Time TrialRunning PerformanceImproves (the measure goes up)
  • Power OutputCycling PerformanceImproves (the measure goes up)
  • Exercise Recovery MarkersMuscle RecoveryImproves (the measure goes up)

Shop Betalains

Third-party tested Betalains products. The evidence above is limited, so read it before you buy.

  • Grade C

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Studies cited

8 studies from PubMed

  1. Betanin as a multipath oxidative stress and inflammation modulator: a beetroot pigment with protective effects on cardiovascular disease pathogenesisCrit Rev Food Sci Nutr, 2022 · PMID 32960870
  2. Beetroot as a functional food with huge health benefits: Antioxidant, antitumor, physical function, and chronic metabolomics activityFood Sci Nutr, 2021 · PMID 34760270
  3. Possible Effects of Beetroot Supplementation on Physical Performance Through Metabolic, Neuroendocrine, and Antioxidant Mechanisms: A Narrative Review of the LiteratureAntioxidants (Basel), 2021 · PMID 34055855
  4. Effect of 1-week betalain-rich beetroot concentrate supplementation on cycling performance and select physiological parametersEur J Appl Physiol, 2018 · PMID 30155761
  5. Betalain-rich concentrate supplementation improves exercise performance and recovery in competitive triathletesAppl Physiol Nutr Metab, 2017 · PMID 28177705
  6. Betalain-Rich Concentrate Supplementation Improves Exercise Performance in Competitive RunnersSports (Basel), 2016 · PMID 29910288
  7. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exerciseEur J Appl Physiol, 2016 · PMID 26537365
  8. Betalains--a new class of dietary cationized antioxidantsJ Agric Food Chem, 2001 · PMID 11714300