Supplement
Apigenin is a flavonoid, a natural plant pigment found in chamomile, parsley and celery. People mostly look at it for mood and sleep, and anxiety symptoms decreased moderately in trials of a chamomile extract containing apigenin, involving 179 people, though the evidence is limited. Those studies tested the whole extract rather than apigenin alone, and sleep gains were small, so it is hard to say how much apigenin itself contributed.
- Updated
- How we grade
- Best evidence
- Grade C
- Conditions studied
- 3
- Outcomes
- 4
- Graded outcomes
- 0031
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Anxiety Symptoms Moderate Decrease (via chamomile extract containing apigenin) | Improves (the measure goes down) | Moderate effect | 179 people |
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Sleep Quality Small Improvement (chamomile extract studies) | Improves (the measure goes up) | Small effect | 120 people | |||
| Daytime Functioning Trend toward improvement, not statistically significant | Improves (the measure goes up) | Small effect | 34 people |
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Depression Symptoms Moderate Decrease in Hamilton Depression Rating Scale | Improves (the measure goes down) | Moderate effect | 57 people |
Key findings
- Anxiety SymptomsImproves (the measure goes down)
- Sleep QualityImproves (the measure goes up)
- Depression SymptomsImproves (the measure goes down)
Shop Apigenin
Third-party tested Apigenin products. The evidence above is limited, so read it before you buy.
- Grade C
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