Supplement
1,3-Dimethylamylamine, often called DMAA, is a stimulant compound that acts on the nervous system and appears in some pre-workout products, with no nutritional role in the body. In a small study of healthy adults, blood pressure went up moderately, an unwelcome effect, while heart rate showed no significant change. That work involved only about ten people, so the evidence is very limited and says little beyond that.
Sources: PMID 22030947
- Updated
- How we grade
- Best evidence
- Grade D
- Conditions studied
- 1
- Outcomes
- 2
- Graded outcomes
- 0002
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
General Cardiovascular Health
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Heart Rate No significant effect on heart rate in small study | NoneNo effect | 1 study | 10 people | |||
Studies that measured heart rate | ||||||
| Blood Pressure Moderate increase in blood pressure (harmful effect) | Improves (the measure goes down) | Moderate effect | 10 people | |||
Key findings
- Heart Rate
- Blood PressureImproves (the measure goes down)
Shop 1,3-Dimethylamylamine
Third-party tested 1,3-Dimethylamylamine products. The evidence above is limited, so read it before you buy.
- Grade D
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