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Dr. Grey AI

Protocol · Autoimmune/Musculoskeletal Disorders

Myositis Supportive Care Protocol

Vitamin D and Creatine Monohydrate are the core of this stack, with 4 supporting supplements. Each row gives the amount the protocol lists and the grade our evidence database holds for that supplement in Myositis Supportive Care.

We are re-verifying the studies cited on protocol pages; only confirmed citations are shown.

The stack

6 supplements · none graded yet

Amount listed in this protocol; not a recommendation.

Supplements in the Myositis Supportive Care protocol, with the amount the protocol lists, the grade on file and confirmed studies
GradeSupplementAmount listedWhy it’s in the stackEvidence on fileShop
Primary stackThe core of this protocol
Vitamin DAmount listed: 2,000–4,000 IU daily (titrate to levels)

Often deficient in autoimmune diseases; supports immune modulation and muscle function

Not graded yet
Creatine MonohydrateAmount listed: 5–10 g daily

Supports muscle energy and may help maintain muscle mass during disease activity

Not graded yet
Supporting stackListed as additions to the core
Omega-3 Fatty AcidsAmount listed: 2–4 g EPA+DHA daily

Anti-inflammatory properties; may help modulate immune response

Not graded yet
Coenzyme Q10Amount listed: 100–300 mg daily

Supports mitochondrial function in muscle cells; antioxidant

Not graded yet
CalciumAmount listed: 1,000–1,200 mg daily

Supports bone health; corticosteroid treatment increases osteoporosis risk

Not graded yet
ProteinAmount listed: 1.2–1.5 g/kg/day total protein

Supports muscle protein synthesis and maintenance during inflammatory states

Not graded yet

Shop the evidence-backed picks

Support alongside medical care. These supplements are not a treatment for Myositis. If you are being treated for it, talk to your clinician before adding one: supplements can interact with medicines.

Fullscript collectionMuscle, performance and healthy ageing: evidence-graded picksOpen on Fullscript

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Each opens third-party tested products, matched to the dose above where we can.

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How this protocol works

In plain language

Myositis refers to a group of rare conditions characterized by chronic muscle inflammation, leading to muscle weakness. The main types are dermatomyositis, polymyositis, and inclusion body myositis.

TYPES:

  • Dermatomyositis: Muscle weakness + skin rash
  • Polymyositis: Muscle weakness without rash
  • Inclusion Body Myositis (IBM): Slowly progressive; often older adults
  • Juvenile myositis: Occurs in children

SYMPTOMS:

  • Progressive muscle weakness (proximal muscles)
  • Difficulty climbing stairs, rising from chairs
  • Difficulty lifting arms overhead
  • Fatigue
  • Skin rashes (dermatomyositis)
  • Swallowing difficulties
  • Shortness of breath (if respiratory muscles affected)

CRITICAL: Myositis requires comprehensive medical management. This protocol is SUPPORTIVE ONLY.

MEDICAL TREATMENTS:

  • Corticosteroids: First-line (prednisone)
  • Immunosuppressants: Methotrexate, azathioprine, mycophenolate
  • IVIG: For refractory cases
  • Rituximab: For difficult cases
  • Physical therapy: Essential for maintaining function

ASSOCIATED CONDITIONS:

  • Interstitial lung disease (requires monitoring)
  • Increased cancer risk (dermatomyositis in adults)
  • Cardiac involvement (possible)
  • Calcinosis (especially in children)

MONITORING:

  • Muscle enzymes (CK, aldolase)
  • Pulmonary function tests
  • Cancer screening (dermatomyositis)
  • Bone density (if on steroids)

Vitamin D* supports muscle function and immune modulation.

Calcium* is important for bone health on corticosteroids.

Adequate protein* helps maintain muscle mass.

Expected timeline: Medical treatment response varies (weeks to months). Supplements support overall health during treatment.

Printed from drgrey.ai/protocols/myositis. For education only; not medical advice. Talk to a clinician before starting any supplement.