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Protocol · Digestive Health

Constipation-Predominant Irritable Bowel Syndrome (IBS-C) Supportive Care Protocol

Psyllium Fiber and Probiotics are the core of this stack, with 6 supporting supplements. Each row gives the amount the protocol lists and the grade our evidence database holds for that supplement in Constipation-Predominant Irritable Bowel Syndrome (IBS-C) Supportive Care.

We are re-verifying the studies cited on protocol pages; only confirmed citations are shown.

The stack

8 supplements · none graded yet

Amount listed in this protocol; not a recommendation.

Supplements in the Constipation-Predominant Irritable Bowel Syndrome (IBS-C) Supportive Care protocol, with the amount the protocol lists, the grade on file and confirmed studies
GradeSupplementAmount listedWhy it’s in the stackEvidence on fileShop
Primary stackThe core of this protocol
Psyllium FiberAmount listed: 5–10 g daily in divided doses, gradually increased; with plenty of water

Soluble fiber that adds bulk and softens stool; best-studied fiber for IBS-C

Not graded yet
ProbioticsAmount listed: 10–50 billion CFU daily (Bifidobacterium infantis 35,624, B. lactis DN-173 010)

Restore gut microbiome balance; specific strains shown to help IBS symptoms

Not graded yet
Supporting stackListed as additions to the core
Peppermint Oil (Enteric-Coated)Amount listed: 180–225 mg enteric-coated capsules 2–3 times daily before meals

Antispasmodic that relaxes intestinal smooth muscle; reduces abdominal pain

Not graded yet
MagnesiumAmount listed: 300–500 mg magnesium citrate or oxide daily

Osmotic laxative effect; also supports muscle relaxation and reduces stress

Not graded yet
Partially Hydrolyzed Guar Gum (PHGG)Amount listed: 5 g daily mixed with liquid

Prebiotic fiber that improves stool consistency and supports beneficial bacteria

Not graded yet
TriphalaAmount listed: 500–1,000 mg before bed

Ayurvedic herbal combination with gentle laxative and gut-supportive effects

Not graded yet
Vitamin DAmount listed: 2,000–4,000 IU daily

Deficiency associated with IBS; supplementation may improve symptoms

Not graded yet
Aloe VeraAmount listed: 100–200 mg aloe vera latex or 50 mL juice daily (short-term)

Contains compounds with laxative effects; may help IBS-C symptoms

Not graded yet

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How this protocol works

In plain language

IBS-C is a functional bowel disorder characterized by chronic abdominal pain associated with constipation (hard or lumpy stools, straining, incomplete evacuation, infrequent bowel movements). Unlike regular constipation, IBS-C involves recurring abdominal pain that relates to bowel movements. It affects quality of life significantly and can be frustrating to manage. The gut-brain connection is central to IBS - stress and emotions affect gut function, and gut symptoms affect mood.

CRITICAL: IBS is a diagnosis of exclusion - make sure other conditions (celiac disease, inflammatory bowel disease, thyroid problems, colon cancer in appropriate age groups) have been ruled out. See a doctor for new symptoms, warning signs (blood in stool, unexplained weight loss, family history of colon cancer, onset after age 50, progressive worsening). Treatment often involves a combination of dietary changes (low FODMAP diet can be very helpful), stress management, and sometimes medications (linaclotide, lubiprostone, plecanatide are FDA-approved for IBS-C). These supplements support management alongside these approaches.

Psyllium Fiber* is the best-studied fiber for IBS-C. It's a soluble fiber that forms a gel, adding bulk and softening stool without causing as much gas as insoluble fiber. Start slowly and increase gradually.

Probiotics* help rebalance the gut microbiome. Certain strains like Bifidobacterium infantis 35624 have been specifically shown to help IBS symptoms.

Peppermint Oil (enteric-coated)* is an antispasmodic that relaxes intestinal muscles, reducing cramping and pain. The enteric coating protects it until it reaches the intestines.

Magnesium* has a natural osmotic laxative effect and also helps with stress and muscle relaxation.

Partially Hydrolyzed Guar Gum* is a prebiotic fiber that improves stool consistency with less bloating than some other fibers.

Triphala* is a traditional Ayurvedic formula with gentle laxative effects.

Vitamin D* deficiency is common in IBS patients, and supplementation may improve symptoms.

Aloe Vera* has laxative properties but should be used cautiously and not long-term.

Expected timeline: Fiber and probiotics may take 2-4 weeks to show benefit. Peppermint oil works more quickly for pain relief. Full benefit often requires 4-12 weeks of consistent use.

Printed from drgrey.ai/protocols/constipation-predominant-irritable-bowel-syndrome-ibs-c. For education only; not medical advice. Talk to a clinician before starting any supplement.