Protocol · Mental Health & Mood
Agoraphobia Supportive Care Protocol
Inositol and Lavender Oil (Silexan) are the core of this stack, with 7 supporting supplements. Each row gives the amount the protocol lists and the grade our evidence database holds for that supplement in Agoraphobia Supportive Care.
We are re-verifying the studies cited on protocol pages; only confirmed citations are shown.
The stack
9 supplements · 2 graded · 1 confirmed study
| Grade | Supplement | Amount listed | Why it’s in the stack | Evidence on file | Shop |
|---|---|---|---|---|---|
| Primary stackThe core of this protocol | |||||
| Inositol | Amount listed: 12–18 g daily in divided doses (start lower, titrate up) | Acts as second messenger in serotonin system; reduces panic and anxiety symptoms which often accompany agoraphobia
| Grade C for Anxiety Symptoms3 studies · 21 people | ||
Confirmed studies for Inositol (titles as PubMed lists them) | |||||
| Lavender Oil (Silexan) | Amount listed: 80–160 mg Silexan (standardized lavender oil) daily | Anxiolytic effects comparable to low-dose benzodiazepines without sedation or dependence | Not graded yet | ||
| Supporting stackListed as additions to the core | |||||
| Kava | Amount listed: 100–250 mg kavalactones daily (use only noble kava, limit duration) | GABAergic herb with proven anxiolytic effects; may help with anticipatory anxiety
| Grade C for Aggression141 people | ||
| Magnesium | Amount listed: 300–400 mg daily (glycinate for calming effects) | Calming effect on nervous system; helps with anxiety and stress symptoms | Not graded yet | ||
| L-Theanine | Amount listed: 100–400 mg as needed or daily | Promotes calm without sedation; can be used as needed before anxiety-provoking situations | Not graded yet | ||
| Passionflower | Amount listed: 250–500 mg extract daily or as needed | GABA-ergic herb with anxiolytic effects; may help with acute anxiety | Not graded yet | ||
| Ashwagandha | Amount listed: 300–600 mg standardized extract daily | Adaptogen that reduces cortisol and chronic stress; may help with underlying anxiety | Not graded yet | ||
| Omega-3 Fatty Acids | Amount listed: 2–3 g EPA+DHA daily (higher EPA for mood) | Anti-inflammatory effects on brain; may reduce anxiety symptoms | Not graded yet | ||
| Vitamin D | Amount listed: 2,000–4,000 IU daily (target 40–60 ng/mL) | Deficiency associated with anxiety disorders; supports overall mental health | Not graded yet | ||
Shop the evidence-backed picks
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Each opens third-party tested products, matched to the dose above where we can.
- Grade C
- Grade C
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How this protocol works
In plain language
Agoraphobia is an anxiety disorder characterized by intense fear and avoidance of situations where escape might be difficult or help unavailable during a panic attack or anxiety symptoms. Common feared situations include public transportation, open spaces, enclosed spaces (like stores), crowds, or being outside the home alone. People with agoraphobia often restrict their activities significantly, and severe cases can lead to being housebound. Agoraphobia frequently occurs with panic disorder but can exist independently.
CRITICAL: Agoraphobia is highly treatable with proper therapy. Cognitive Behavioral Therapy (CBT) with exposure therapy is the gold standard - it teaches you to gradually face feared situations while managing anxiety. SSRIs are also effective. Without treatment, agoraphobia tends to become chronic and disabling. These supplements may help manage anxiety symptoms but should COMPLEMENT, not replace, evidence-based treatment. If you're significantly limiting your activities due to fear, seek professional help.
Inositol* works through the serotonin system similar to SSRIs. It has been specifically studied for panic disorder with agoraphobia and can significantly reduce both panic attacks and agoraphobic avoidance. High doses (12-18g) are needed.
Lavender Oil (Silexan)* has proven anxiolytic effects without the sedation or dependence risk of benzodiazepines. It can help reduce general anxiety levels.
Kava* is a Pacific Island herb with GABAergic effects that reduce anxiety. A Cochrane review confirmed its effectiveness for anxiety disorders. Use only noble kava and limit duration due to potential liver effects with long-term use.
Magnesium* has calming effects on the nervous system and is often depleted by chronic stress. Glycinate is preferred for anxiety.
L-Theanine* promotes calm without sedation and can be taken before anxiety-provoking situations. It increases relaxing alpha brain waves.
Passionflower* has GABA-ergic effects that can help with acute anxiety.
Ashwagandha* reduces cortisol and helps with the chronic stress component of anxiety disorders.
Omega-3 Fatty Acids* have anti-inflammatory effects on the brain and may help reduce anxiety.
Vitamin D* deficiency is associated with anxiety disorders. Maintaining adequate levels supports mental health.
Expected timeline: Inositol: 4-8 weeks for full effect. Lavender and kava: 2-4 weeks. L-theanine works acutely. CBT with exposure therapy typically shows improvement over 12-16 sessions. Full recovery from agoraphobia often takes several months of consistent therapy.