Condition
Purine Metabolism
Purine metabolism is how the body makes and breaks down purines, the building blocks of DNA and RNA, with the enzyme xanthine oxidase helping turn them into uric acid. Molybdenum, a mineral that enzyme relies on, has moderate evidence, and studies found xanthine oxidase activity went up. That rests on about 150 participants and measured the enzyme itself, so it says little yet about uric acid or how people felt.
- Updated
- How we grade
- 10 studies cited
- Supplements studied
- 1
- Graded outcomes
- 1
Evidence by supplement
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Xanthine Oxidase Activity Moderate Increase | Improves (the measure goes up) | Moderate effect | 150 people |
Key findings
- Xanthine Oxidase ActivityImproves (the measure goes up)
Shop the evidence-backed picks
The collection holds the supplements we grade A or B for its theme, in third-party tested products where the catalog has them. It opens in our Fullscript store. You can look through it without signing in; Fullscript asks for a free account to order.
Or shop one supplement
The supplement graded A or B for Purine Metabolism. Each opens third-party tested products for that supplement.
- Grade B
We earn from purchases made in our Fullscript store, and links to Fullscript, iHerb or Thorne carry our referral, so we may earn a commission at no extra cost to you. Grades come from the research and never change based on what we earn. Full disclosure
Studies cited
10 studies from PubMed
- Molybdenum Cofactor Deficiency: Clinical Presentations and Management
- Molybdenum and Sulfite Metabolism: Biochemistry and Clinical Relevance
- Molybdenum-Containing Enzymes in Human Metabolism
- Role of Molybdenum in Xanthine Oxidase Function
- Upper Tolerable Limits of Molybdenum: Safety Considerations
- Molybdenum in Human Health: A Review of Essential Functions
- Dietary Molybdenum Intake: Sources and Recommendations
- Molybdenum Status Assessment: Biomarkers and Methods
- Molybdenum: Dietary Requirements and Deficiency
- Molybdenum Toxicity and Deficiency: A Review of Clinical Cases