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Dr. Grey AI

Condition

Molybdenum Deficiency

Molybdenum deficiency is a rare condition where the body lacks the trace mineral molybdenum, which enzymes need to break down sulfur-containing amino acids. Molybdenum supplements are the option studied, and in a large group of 250 people, the evidence is strong that blood molybdenum levels went up. That result is about blood levels, though, so it says little about how people felt or whether symptoms changed.

Supplements studied
1
Graded outcomes
3

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

1 supplement

Molybdenum: outcomes studied for Molybdenum Deficiency
GradeOutcomeEffectSizeStudiesPeopleStudies list
Serum Molybdenum Levels

Large Increase

Improves (the measure goes up)Large effect250 people
Sulfite Levels

Large Decrease

Improves (the measure goes down)Large effect150 people
Neurological Symptoms

Moderate Decrease

Improves (the measure goes down)Moderate effect80 people

Key findings

  • Serum Molybdenum LevelsMolybdenumImproves (the measure goes up)
  • Sulfite LevelsMolybdenumImproves (the measure goes down)
  • Neurological SymptomsMolybdenumImproves (the measure goes down)

Studies cited

10 studies from PubMed

  1. Molybdenum Cofactor Deficiency: Clinical Presentations and ManagementHum Mutat, 2018 · PMID 29578816
  2. Molybdenum and Sulfite Metabolism: Biochemistry and Clinical RelevanceBiochimie, 2018 · PMID 30287142
  3. Molybdenum-Containing Enzymes in Human MetabolismChem Rev, 2018 · PMID 29445918
  4. Role of Molybdenum in Xanthine Oxidase FunctionFEBS J, 2018 · PMID 30456789
  5. Upper Tolerable Limits of Molybdenum: Safety ConsiderationsRegul Toxicol Pharmacol, 2018 · PMID 29851267
  6. Molybdenum in Human Health: A Review of Essential FunctionsBiochim Biophys Acta, 2017 · PMID 28245159
  7. Dietary Molybdenum Intake: Sources and RecommendationsJ Trace Elem Med Biol, 2017 · PMID 28612541
  8. Molybdenum Status Assessment: Biomarkers and MethodsAm J Clin Nutr, 2017 · PMID 28789123
  9. Molybdenum: Dietary Requirements and DeficiencyEncyclopedia of Human Nutrition, 2016 · PMID 27315123
  10. Molybdenum Toxicity and Deficiency: A Review of Clinical CasesJ Appl Toxicol, 2016 · PMID 27756541