Condition
Dermatitis
Dermatitis, or eczema, is inflamed, red, itchy, dry skin, and the common atopic type often runs in families with allergies and asthma. Probiotics and vitamin D have the most research behind them, rated moderate, and hyaluronic acid improved skin severity in people having radiotherapy. Evidence for evening primrose oil, omega-3s and zinc is limited, and the hyaluronic acid result came from one analysis of 104 people, not everyday eczema.
Sources: PMID 35152333
- Supplements studied
- 3
- Graded outcomes
- 3
- Trials
- 4
- People studied
- 1,895
Evidence by supplement
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Dermatitis Severity Moderate Improvement | Improves (the measure goes down) | Moderate effect | 1 study | 104 people | ||
Studies that measured dermatitis severity | ||||||
| Mucositis Symptoms | Improves (the measure goes down) | 107 people | ||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Dermatitis Risk Small Improvement | Improves (the measure goes down) | Small effect | 3 studies | 756 people | ||
Studies that measured dermatitis risk
| ||||||
| Itching Mixed effect | 420 people | |||||
| Pain | Changes; see studies | 420 people | ||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Erythema | Improves (the measure goes up) | 1 study | 8 people | |||
Studies that measured erythema | ||||||
Key findings
- Dermatitis SeverityImproves (the measure goes down)
- Dermatitis RiskImproves (the measure goes down)
- Itching
The Dermatitis (Eczema) Support protocol
2 primary supplements · 3 supporting supplements
- Probiotics10–20 billion CFU daily (Lactobacillus and Bifidobacterium strains)
- Vitamin D2,000–4,000 IU daily
Shop the evidence-backed picks
The collection holds the supplements we grade A or B for its theme, in third-party tested products where the catalog has them. It opens in our Fullscript store. You can look through it without signing in; Fullscript asks for a free account to order.
Or shop one supplement
The supplement graded A or B for Dermatitis. Each opens third-party tested products for that supplement.
- Grade B
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Studies cited
19 studies from PubMed
- The effect of versus metronidazole on bacterial vaginosis in women: A double-blind randomized controlled trial.
- Therapeutic effectiveness of a Calendula officinalis extract in venous leg ulcer healing.
- Evaluation of Calendula officinalis as an anti-plaque and anti-gingivitis agent.
- Comparing the effects of Calendula officinalis and clotrimazole on vaginal Candidiasis: A randomized controlled trial.
- Treatment of acute wounds in hand with L.: A randomized trial.
- Antioxidant capacity of calendula officinalis flowers extract and prevention of radiation induced oropharyngeal mucositis in patients with head and neck cancers: a randomized controlled clinical study.
- No differences between Calendula cream and aqueous cream in the prevention of acute radiation skin reactions--results from a randomised blinded trial.
- Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer.
- Use of calendula ointment after episiotomy: a randomized clinical trial.
- Low-level laser therapy and Calendula officinalis in repairing diabetic foot ulcers.
- Calendula extract: effects on mechanical parameters of human skin.
- Feverfew in rheumatoid arthritis: a double blind, placebo controlled study
- Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)
- Efficacy of feverfew as prophylactic treatment of migraine
- The efficacy and safety of Tanacetum parthenium (feverfew) in migraine prophylaxis--a double-blind, multicentre, randomized placebo-controlled dose-response study
- Randomised double-blind placebo-controlled trial of feverfew in migraine prevention
- Efficacy and safety of 6.25 mg t.i.d. feverfew CO2-extract (MIG-99) in migraine prevention--a randomized, double-blind, multicentre, placebo-controlled study
- Effect of hyaluronic acid on radiotherapy-induced mucocutaneous side effects: a meta-analysis of randomized controlled trials.
- A Meta-Analysis of the Efficacy of Hyaluronic Acid Eye Drops for the Treatment of Dry Eye Syndrome