Dermatitis

Dermatitis is an umbrella term used to describe skin inflammation from conditions such as eczema, contact dermatitis, and seborrheic dermatitis. Symptoms of these conditions include dry skin, redness, and itchiness.

Quick Answer

What it is

Key findings

Grade B: Dermatitis Severity (Hyaluronic Acid)
Grade C: Dermatitis Risk (Calendula Officinalis)
Grade C: Itching (Calendula Officinalis)

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts

Quick Facts: Dermatitis

Supplements Studied:3
Research Trials:4
Total Participants:1,895
Top Supplement:Hyaluronic Acid (B)

4 trials

1,895 participantsppts

3 supps · 6 outcomes

Evidence-Based Protocol

Supplement stack ranked by research quality

Moderate Evidence

Primary Stack (Tier 1)

ProbioticsB

10-20 billion CFU daily (Lactobacillus and Bifidobacterium strains)

May help modulate immune response; evidence for prevention and treatment

20 studies | 1,500 participants

Vitamin DB

2000-4000 IU daily

Supports skin barrier function and immune modulation; deficiency linked to eczema severity

12 studies | 800 participants

Supporting Stack (Tier 2)

Evening Primrose OilC

3-6g daily

GLA may help skin barrier function; mixed evidence

10 studies | 500 participants

Omega-3 Fatty AcidsC

2-3g EPA+DHA daily

Anti-inflammatory; supports skin health

8 studies | 400 participants

ZincC

15-30mg daily

Supports skin healing and immune function

5 studies | 200 participants

How It Works

Dermatitis (eczema) is an inflammatory skin condition causing red, itchy, dry skin. Atopic dermatitis is the most common type and often runs in families with allergies and asthma.

TYPES:

•Atopic dermatitis (most common)

•Contact dermatitis (allergic or irritant)

•Seborrheic dermatitis (scalp, face)

•Nummular dermatitis (coin-shaped patches)

SYMPTOMS:

•Itching (often severe)

•Red, dry, scaly skin

•Patches on face, inside elbows, behind knees

•Thickened skin from scratching

•Oozing and crusting in flares

MANAGEMENT:

•Moisturize frequently (most important!)

•Avoid triggers (soaps, allergens, irritants)

•Topical corticosteroids for flares

•Topical calcineurin inhibitors

•Wet wraps for severe cases

•Biologics (dupilumab) for moderate-severe

* Probiotics may help, especially in children.

* Vitamin D deficiency is linked to severity.

* Moisturizing is cornerstone of treatment.

Expected timeline: Supplements may take 2-3 months to show benefit. Consistent moisturizing provides ongoing protection.

Generated from peer-reviewed researchSchema v2.0

Supplements for Dermatitis

Sorted by strength of evidence

BHyaluronic Acid

1 outcome · 4 studies

↓Dermatitis SeverityImproves↓Mucositis SymptomsImproves

CCalendula Officinalis

1 outcome · 5 studies

↓Dermatitis RiskImprovesItching↑PainWorsens

Detailed Outcomes

Dermatitis Severity

Moderate Improvement

2 studies104 participants

moderate↓Improves

Mucositis Symptoms

2 studies107 participants

↓Improves

Dermatitis Risk

Small Improvement

3 studies756 participants

small↓Improves

Itching

Mixed effect

1 study420 participants

Pain

1 study420 participants

↑Worsens

Erythema

1 study8 participants

↑Improves

Research Citations (19)

The effect of versus metronidazole on bacterial vaginosis in women: A double-blind randomized controlled trial.

J Adv Pharm Technol Res

PMID: 29441319

Therapeutic effectiveness of a Calendula officinalis extract in venous leg ulcer healing.

J Wound Care

PMID: 27974009

Evaluation of Calendula officinalis as an anti-plaque and anti-gingivitis agent.

J Indian Soc Periodontol

PMID: 24554883

Comparing the effects of Calendula officinalis and clotrimazole on vaginal Candidiasis: A randomized controlled trial.

Women Health

PMID: 27880086

Treatment of acute wounds in hand with L.: A randomized trial.

Tissue Barriers

PMID: 34674610

Antioxidant capacity of calendula officinalis flowers extract and prevention of radiation induced oropharyngeal mucositis in patients with head and neck cancers: a randomized controlled clinical study.

Daru

PMID: 23497687

No differences between Calendula cream and aqueous cream in the prevention of acute radiation skin reactions--results from a randomised blinded trial.

Eur J Oncol Nurs

PMID: 23245940

Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer.

J Clin Oncol

PMID: 15084618

Use of calendula ointment after episiotomy: a randomized clinical trial.

J Matern Fetal Neonatal Med

PMID: 32460565

Low-level laser therapy and Calendula officinalis in repairing diabetic foot ulcers.

Rev Esc Enferm USP

PMID: 27680049

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