Supplement
Trehalose is a natural sugar made of two linked glucose molecules, found in mushrooms, yeast and some plants, where it helps cells withstand drying and oxidative stress. Most people look at it for dry eye, and the evidence is moderate: in two trials of eye drops, dry eye symptoms improved. Those studies were small, involving only 70 people in total, so the findings are early and say little about long-term use.
Sources: PMID 12414409; PMID 15295655
- Updated
- How we grade
- 2 studies cited
- Best evidence
- Grade B
- Conditions studied
- 1
- Outcomes
- 1
- Graded outcomes
- 0100
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Dry Eye Symptoms Large Improvement | Improves (the measure goes down) | Large effect | 2 studies | 70 people | ||
Studies that measured dry eye symptoms | ||||||
Key findings
- Dry Eye SymptomsImproves (the measure goes down)
Shop the evidence-backed picks
Third-party tested Trehalose products, in the forms the graded studies used where we can match them.
- Grade B
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Studies cited
2 studies from PubMed