Supplement
Safed musli is a root used in traditional Indian herbal medicine, rich in saponins and polysaccharides. People mostly look at it for sexual function and libido, and the evidence is limited: multiple rodent studies consistently found dose-dependent aphrodisiac effects, including more mating behavior. Human data is scarce and muddied because trials used combination formulas and had industry funding, so effects of safed musli alone remain unclear.
Sources: PMID 19751181; PMID 24045177
- Updated
- How we grade
- 2 studies cited
- Best evidence
- Grade C
- Conditions studied
- 1
- Outcomes
- 6
- Graded outcomes
- 0015
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
General
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Sexual Function & Libido Multiple rodent studies consistently demonstrate dose-dependent aphrodisiac effects including increased mounting frequency, intromission frequency, and ejaculation latency improvements. Limited human data exists but is confounded by combination formulations and industry funding. | Improves (the measure goes up) | Moderate effect | 2 studies | |||
| Erectile Function In rodent models, Chlorophytum borivilianum root extract improved erectile response parameters in a dose-dependent manner. No controlled human studies have isolated its erectogenic effects independent of combination products. | Improves (the measure goes up) | Moderate effect | 2 studies | |||
| Testosterone Levels Rodent studies report increases in serum testosterone levels following Chlorophytum borivilianum supplementation. Human evidence is lacking; existing human trials used multi-herb combinations, preventing attribution to safed musli alone. | Improves (the measure goes up) | Small effect | 2 studies | |||
| Sperm Parameters In rodent models, safed musli root extract improved sperm count, motility, and morphology. These findings suggest potential male fertility benefits, but no controlled human trials have confirmed these effects. | Improves (the measure goes up) | Moderate effect | 2 studies | |||
| Immune Function Early preclinical studies indicate immunomodulatory properties of safed musli polysaccharides. Evidence remains preliminary with no human data available. | Improves (the measure goes up) | Small effect | 1 study | |||
Studies that measured immune function | ||||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Antioxidant Status Preclinical studies report antioxidant activity of Chlorophytum borivilianum extracts, attributed to its saponin and polysaccharide content. Evidence is limited to in vitro and early animal models. | Improves (the measure goes up) | Small effect | 1 study | |||
Studies that measured antioxidant status | ||||||
Key findings
- Sexual Function & LibidoImproves (the measure goes up)
- Erectile FunctionImproves (the measure goes up)
- Testosterone LevelsImproves (the measure goes up)
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- Grade C
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Studies cited
2 studies from PubMed