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Dr. Grey AI

Supplement

Octopamine

Octopamine is a trace amine, a compound chemically related to the stress messenger norepinephrine, made in small amounts in the body and found in some plants. People have looked at it mainly for urinary incontinence, and the evidence is moderate: in three trials, signs of incontinence improved. Those studies were small, with 97 participants in total, and tested norfenefrine, a close relative, in women with stress incontinence.

Sources: PMID 3287737; PMID 6150569

Best evidence
Grade B
Conditions studied
1
Outcomes
1
Graded outcomes
0100

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

1 condition

Urinary Incontinence: outcomes studied for Octopamine
GradeOutcomeEffectSizeStudiesPeopleStudies list
Urinary Incontinence Signs

Small Improvement

Improves (the measure goes up)Small effect3 studies97 people

Key findings

  • Urinary Incontinence SignsUrinary IncontinenceImproves (the measure goes up)

Shop the evidence-backed picks

Third-party tested Octopamine products, in the forms the graded studies used where we can match them.

  • Grade B

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Studies cited

3 studies from PubMed

  1. Norfenefrine in the treatment of female stress incontinence. A double-blind controlled trialUrol Int · PMID 3287737
  2. Clinical and urodynamic effects of norfenefrine in women with stress incontinenceUrol Int · PMID 6150569
  3. Norfenefrine in the treatment of female urinary stress incontinence assessed by one-hour pad weighing testUrol Int · PMID 2568712