Condition
Urinary Incontinence
Urinary incontinence is the involuntary leakage of urine, caused either by a weak pelvic floor that gives way under pressure or by a bladder that signals a sudden, hard-to-control urge. Among supplements, octopamine has the most trial support, and three small trials found signs of stress incontinence in women eased. Those studies included only 97 people in total, so the evidence is moderate at best, and pelvic floor exercises remain the main approach.
Sources: PMID 3287737; PMID 6150569
- Supplements studied
- 2
- Graded outcomes
- 2
- Trials
- 4
- People studied
- 131
Evidence by supplement
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Urinary Incontinence Signs Small Improvement | Improves (the measure goes up) | Small effect | 3 studies | 97 people | ||
Studies that measured urinary incontinence signs | ||||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Blood Pressure Small Improvement | Improves (the measure goes down) | Small effect | 1 study | 34 people | ||
| Cortisol | Improves (the measure goes down) | 34 people | ||||
| Heart Rate | Improves (the measure goes down) | 34 people | ||||
Key findings
- Urinary Incontinence SignsImproves (the measure goes up)
- Blood PressureImproves (the measure goes down)
The Urinary Incontinence Support protocol
2 primary supplements · 6 supporting supplements
- Pumpkin Seed Extract500–1,000 mg daily (standardized extract)
- Vitamin D2,000–4,000 IU daily (target 40–60 ng/mL)
Shop the evidence-backed picks
The supplement graded A or B for Urinary Incontinence. Each opens third-party tested products for that supplement.
- Grade B
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Studies cited
4 studies from PubMed
- Randomized Controlled Trial for Salvia sclarea or Lavandula angustifolia: Differential Effects on Blood Pressure in Female Patients with Urinary Incontinence Undergoing Urodynamic Examination
- Norfenefrine in the treatment of female stress incontinence. A double-blind controlled trial
- Clinical and urodynamic effects of norfenefrine in women with stress incontinence
- Norfenefrine in the treatment of female urinary stress incontinence assessed by one-hour pad weighing test