Multivitamin
Multivitamins are the most commonly used supplement category. CRITICAL REALITY CHECK: Large RCTs and meta-analyses show NO significant benefit for cardiovascular disease, cancer prevention, or mortality in well-nourished populations. The Physicians' Health Study II (n=14,641) found no CVD benefit. COSMOS-Mind showed no cognitive benefit. May benefit those with documented deficiencies, malabsorption, restricted diets, or pregnancy. The 'insurance policy' marketing is not supported by evidence for healthy, well-fed individuals.
Quick Answer
What it is
Multivitamins are the most commonly used supplement category. CRITICAL REALITY CHECK: Large RCTs and meta-analyses show NO significant benefit for cardiovascular disease, cancer prevention, or mortality in well-nourished populations.
Key findings
- Grade A: Neural Tube Defects
- Grade C: ADHD Symptoms
- Grade D: All-Cause Mortality
Safety
No specific caution or interaction language was detected in the current summary/outcome notes.
ℹ️ Quick Facts: Multivitamin
Quick Facts: Multivitamin
- Best Evidence:Grade D
- Conditions Studied:2
- Research Outcomes:6
- Grade A Findings:1
- Key Effect:Cardiovascular Disease
Detailed Outcomes
Evidence by Condition
Best grade per condition (each condition may have multiple outcomes)
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