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Dr. Grey AI

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Jiaogulan

Jiaogulan is a climbing vine whose leaves contain gypenosides, plant compounds thought to influence how the body handles sugar and fat. People mostly look at it for blood sugar in type 2 diabetes, and moderate evidence from a study of 49 people found blood glucose came down. Studies so far are small, and a 56-person fatty liver study found better blood sugar control too, but that evidence is limited.

Best evidence
Grade B
Conditions studied
2
Outcomes
11
Graded outcomes
0120

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

2 conditions

Type 2 Diabetes

Type 2 Diabetes: outcomes studied for Jiaogulan
GradeOutcomeEffectSizeStudiesPeopleStudies list
Blood glucose

Moderate Improvement

Improves (the measure goes down)Moderate effect49 people
Glycemic Control

Moderate Improvement

Improves (the measure goes up)Moderate effect24 people
HbA1cImproves (the measure goes down)2 studies49 people

Studies that measured hba1c

High-density lipoprotein (HDL)Improves (the measure goes up)25 people
Low-density lipoprotein (LDL)Improves (the measure goes down)25 people
TriglyceridesImproves (the measure goes down)25 people

Nonalcoholic Fatty Liver Disease (NAFLD)

Nonalcoholic Fatty Liver Disease (NAFLD): outcomes studied for Jiaogulan
GradeOutcomeEffectSizeStudiesPeopleStudies list
Glycemic Control

Moderate Improvement

Improves (the measure goes up)Moderate effect56 people
Uric AcidImproves (the measure goes down)1 study56 people

Studies that measured uric acid

InsulinChanges; see studies56 people
Liver EnzymesChanges; see studies56 people
WeightImproves (the measure goes down)56 people

Key findings

  • Blood glucoseType 2 DiabetesImproves (the measure goes down)
  • Glycemic ControlType 2 DiabetesImproves (the measure goes up)

Shop the evidence-backed picks

Third-party tested Jiaogulan products, in the forms the graded studies used where we can match them.

  • Grade B

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Studies cited

3 studies from PubMed

  1. Antidiabetic effect of Gynostemma pentaphyllum tea in randomly assigned type 2 diabetic patientsHorm Metab Res · PMID 20213586
  2. Antidiabetic Effects of Add-On Gynostemma pentaphyllum Extract Therapy with Sulfonylureas in Type 2 Diabetic PatientsEvid Based Complement Alternat Med · PMID 23125867
  3. The add-on effects of Gynostemma pentaphyllum on nonalcoholic fatty liver diseaseAltern Ther Health Med · PMID 16708768