Caesalpinia Benthamiana

Caesalpinia benthamiana is a West African traditional herb used for erectile dysfunction and wound healing. Very preliminary research shows it increases nitric oxide synthase (NOS) expression in endothelial cells and has potent aphrodisiac effects in animal models. Mechanism appears to involve enhanced NO production leading to vasodilation. However, NO human clinical trials exist. Research is extremely limited - mostly animal studies on sexual behavior and in vitro work on endothelial cells.

Quick Answer

What it is

Caesalpinia benthamiana is a West African traditional herb used for erectile dysfunction and wound healing. Very preliminary research shows it increases nitric oxide synthase (NOS) expression in endothelial cells and has potent aphrodisiac effects in animal models.

Key findings

  • Grade D: Sexual Function
  • Grade D: Nitric Oxide Production
  • Grade D: Wound Healing

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts: Caesalpinia Benthamiana

Quick Facts: Caesalpinia Benthamiana

  • Best Evidence:Grade D
  • Conditions Studied:0
  • Research Outcomes:3
Outcomes by grade:
A0
B0
C0
D3
0 conditions · 3 outcomes

Detailed Outcomes

D
Sexual Function
In rodent models, Caesalpinia benthamiana root extract dose-dependently increased mounting frequency, intromission frequency, and ejaculation latency, suggesting potent aphrodisiac activity comparable to or exceeding some reference compounds. No human trials exist.
moderate↑Improves
D
Nitric Oxide Production
In vitro studies on human endothelial cell cultures showed that root extracts increased nitric oxide synthase (NOS) expression, supporting a vasodilation mechanism consistent with the traditional use for erectile dysfunction. No in vivo human data available.
moderate↑Improves
D
Wound Healing
Traditionally prepared as a topical paste for wound treatment. Preliminary in vitro studies suggest antimicrobial activity, but the wound healing effect has not been rigorously characterized in controlled studies.
small↑Improves

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