Boswellia

Boswellia serrata is an Ayurvedic anti-inflammatory herb containing boswellic acids that inhibit 5-lipoxygenase (5-LOX). C-GRADE for asthma symptoms (small improvement, 1 study, 1879 participants) and skin elasticity (small improvement). D-GRADE for CRP (no effect). Used traditionally for osteoarthritis, asthma, and inflammatory conditions. Aflapin and 5-Loxin are standardized extracts with enhanced bioavailability. May improve osteoarthritis symptoms based on preliminary evidence. Relatively safe with good tolerability.

Quick Answer

What it is

Boswellia serrata is an Ayurvedic anti-inflammatory herb containing boswellic acids that inhibit 5-lipoxygenase (5-LOX). C-GRADE for asthma symptoms (small improvement, 1 study, 1879 participants) and skin elasticity (small improvement).

Key findings

  • Grade C: Asthma Symptoms (Osteoarthritis (OA))
  • Grade C: Skin Elasticity (Skin Health)
  • Grade C: Brain Tumor Size (Brain Tumor)

Safety

No specific caution or interaction language was detected in the current summary/outcome notes.

ℹ️ Quick Facts: Boswellia

Quick Facts: Boswellia

  • Best Evidence:Grade C
  • Conditions Studied:4
  • Research Outcomes:10
  • Key Effect:Osteoarthritis (OA)
Outcomes by grade:
A0
B0
C3
D1
4 conditions · 10 outcomes

Detailed Outcomes

|
C
Asthma Symptoms
Small Improvement
smallImproves
D
C-Reactive Protein (CRP)
No effect
1 study
none
?
Osteoarthritis Symptoms
Improvement
Improves
?
Pain
Improvement
3 studies
Improves
?
Interleukin 6
1 study
Worsens
?
Subjective Well-Being
1 study
Improves
C
Skin Elasticity
Small Improvement
smallImproves
?
Skin Quality
1 study
Improves
C
Brain Tumor Size
Moderate Improvement
1 study
moderateImproves
?
Asthma Symptoms
Improvement
Improves

Research Citations (13)

A double blind, randomized, placebo controlled clinical study evaluates the early efficacy of aflapin in subjects with osteoarthritis of knee
PMID: 22022214
Comparative efficacy and tolerability of 5-Loxin and AflapinAgainst osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study
PMID: 21060724
A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee
PMID: 18667054
Clinical evaluation of Boswellia serrata (Shallaki) resin in the management of Sandhivata (osteoarthritis)
PMID: 22661840
A standardized Boswellia serrata extract shows improvements in knee osteoarthritis within five days-a double-blind, randomized, three-arm, parallel-group, multi-center, placebo-controlled trial.
PMID: 39092235
Oral herbal medicines marketed in Brazil for the treatment of osteoarthritis: A systematic review and meta-analysis.
PMID: 28872719
Oral herbal therapies for treating osteoarthritis.
PMID: 24848732
Efficacy of curcumin and Boswellia for knee osteoarthritis: Systematic review and meta-analysis
PMID: 29622343
Efficacy evaluation of standardized Boswellia serrata extract (Aflapin(Ⓡ)) in osteoarthritis: A systematic review and sub-group meta-analysis study.
PMID: 38365549
Efficacy of Extracts of Oleogum Resin of Boswellia in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis.
PMID: 39314013

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