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Boswellia

Boswellia is a resin from the Boswellia tree whose boswellic acids block 5-lipoxygenase, an enzyme that helps produce inflammatory leukotrienes in the body. People look at it mainly as supportive care around brain tumors, where it may reduce swelling, and the reported result was a smaller tumor size, though the evidence is limited. That finding came from a single person, and in osteoarthritis, C-reactive protein showed no clear difference in 98 people.

Sources: PMID 14669258

Best evidence
Grade C
Conditions studied
4
Outcomes
10
Graded outcomes
0031

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

4 conditions

Osteoarthritis (OA): outcomes studied for Boswellia
GradeOutcomeEffectSizeStudiesPeopleStudies list
Asthma Symptoms

Small Improvement

Improves (the measure goes down)Small effect2 studies1,879 people
C-Reactive Protein (CRP)

No effect

NoneNo effect98 people
Osteoarthritis Symptoms

Improvement

Improves (the measure goes down)11 studies186 people

Studies that measured osteoarthritis symptoms

and 1 more in the citations list

Pain

Improvement

Improves (the measure goes down)186 people
Interleukin 6Changes; see studies98 people
Subjective Well-BeingImproves (the measure goes up)47 people

Skin Health: outcomes studied for Boswellia
GradeOutcomeEffectSizeStudiesPeopleStudies list
Skin Elasticity

Small Improvement

Improves (the measure goes up)Small effect1 study15 people
Skin QualityImproves (the measure goes up)15 people

Brain Tumor

  • Brain Tumor Size: improves
Brain Tumor: outcomes studied for Boswellia
GradeOutcomeEffectSizeStudiesPeopleStudies list
Brain Tumor Size

Moderate Improvement

Improves (the measure goes down)Moderate effect1 person

Asthma

  • Asthma Symptoms: improves
Asthma: outcomes studied for Boswellia
GradeOutcomeEffectSizeStudiesPeopleStudies list
Asthma Symptoms

Improvement

Improves (the measure goes down)2 studies80 people

Key findings

  • Asthma SymptomsOsteoarthritis (OA)Improves (the measure goes down)
  • Skin ElasticitySkin HealthImproves (the measure goes up)
  • Brain Tumor SizeBrain TumorImproves (the measure goes down)

Shop Boswellia

Third-party tested Boswellia products. The evidence above is limited, so read it before you buy.

  • Grade C

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Studies cited

13 studies from PubMed

  1. A double blind, randomized, placebo controlled clinical study evaluates the early efficacy of aflapin in subjects with osteoarthritis of kneeInt J Med Sci · PMID 22022214
  2. Comparative efficacy and tolerability of 5-Loxin and AflapinAgainst osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical studyInt J Med Sci · PMID 21060724
  3. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the kneeArthritis Res Ther · PMID 18667054
  4. Clinical evaluation of Boswellia serrata (Shallaki) resin in the management of Sandhivata (osteoarthritis)Ayu · PMID 22661840
  5. A standardized Boswellia serrata extract shows improvements in knee osteoarthritis within five days-a double-blind, randomized, three-arm, parallel-group, multi-center, placebo-controlled trial.Front Pharmacol · PMID 39092235
  6. Oral herbal medicines marketed in Brazil for the treatment of osteoarthritis: A systematic review and meta-analysis.Phytother Res · PMID 28872719
  7. Oral herbal therapies for treating osteoarthritis.Cochrane Database Syst Rev · PMID 24848732
  8. Efficacy of curcumin and Boswellia for knee osteoarthritis: Systematic review and meta-analysisSemin Arthritis Rheum · PMID 29622343
  9. Efficacy evaluation of standardized Boswellia serrata extract (Aflapin(Ⓡ)) in osteoarthritis: A systematic review and sub-group meta-analysis study.Explore · PMID 38365549
  10. Efficacy of Extracts of Oleogum Resin of Boswellia in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis.Phytother Res · PMID 39314013
  11. Herbal interventions for chronic asthma in adults and children: a systematic review and meta-analysis.Prim Care Respir J · PMID 20640388
  12. Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical studyEur J Med Res · PMID 9810030
  13. Effects of topical boswellic acid on photo and age-damaged skin: clinical, biophysical, and echographic evaluations in a double-blind, randomized, split-face studyPlanta Med · PMID 19918712