Rutin
Rutin is a flavonoid glycoside (quercetin + rutinose sugar) found in buckwheat, citrus, and many plants. Hydroxyethylrutosides (HER/Venoruton) are modified derivatives with better absorption. Primary use is for chronic venous insufficiency (CVI) - modest symptom improvement (leg heaviness, cramps, edema) with C-grade evidence. Has antiplatelet and antioxidant properties. Low oral bioavailability limits plain rutin; HER derivatives are preferred. Does NOT reverse varicose veins - only manages symptoms.
Quick Answer
What it is
Rutin is a flavonoid glycoside (quercetin + rutinose sugar) found in buckwheat, citrus, and many plants. Hydroxyethylrutosides (HER/Venoruton) are modified derivatives with better absorption.
Key findings
- Grade C: Leg Symptoms (Chronic Venous Insufficiency)
- Grade C: Edema (Chronic Venous Insufficiency)
- Grade C: LDL Oxidation (Cardiovascular Health)
Safety
No specific caution or interaction language was detected in the current summary/outcome notes.
ℹ️ Quick Facts: Rutin
Quick Facts: Rutin
- Best Evidence:Grade C
- Conditions Studied:3
- Research Outcomes:5
- Key Effect:Chronic Venous Insufficiency
Detailed Outcomes
Evidence by Condition
Best grade per condition (each condition may have multiple outcomes)
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