Supplement
Phenylpiracetam is a lab-made relative of piracetam, a compound thought to influence chemical signaling between brain cells. People mostly look at it for thinking and memory, and in two small trials in people with stroke, cognition improved, though the evidence is limited. Those studies were small, and the results apply mostly to people with brain conditions rather than healthy adults, so they say little about everyday sharpness.
Sources: PMID 18646385; PMID 16608112
- Updated
- How we grade
- 4 studies cited
- Best evidence
- Grade C
- Conditions studied
- 5
- Outcomes
- 9
- Graded outcomes
- 0030
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Cognition Small Improvement | Improves (the measure goes up) | Small effect | 2 studies | 400 people | ||
Studies that measured cognition | ||||||
| Functionality in Elderly or Injured Small Improvement | Improves (the measure goes up) | Small effect | 400 people | |||
| Stroke Recovery | Improves (the measure goes up) | 1 study | 400 people | |||
Studies that measured stroke recovery | ||||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Anxiety Symptoms Small Improvement | Improves (the measure goes down) | Small effect | 99 people | |||
| Depression Symptoms | Improves (the measure goes down) | 1 study | 99 people | |||
Studies that measured depression symptoms | ||||||
| Cognitive Decline | Improves (the measure goes down) | 99 people | ||||
General Cardiovascular Health
- Cognition: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Cognition | Improves (the measure goes up) | 2 studies | 51 people | |||
Studies that measured cognition | ||||||
Epilepsy
- Cognition: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Cognition | Improves (the measure goes up) | 2 studies | 40 people | |||
Studies that measured cognition | ||||||
Traumatic Brain Injury
- Fatigue Symptoms: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Fatigue Symptoms | Improves (the measure goes down) | 56 people |
Key findings
- CognitionImproves (the measure goes up)
- Functionality in Elderly or InjuredImproves (the measure goes up)
- Anxiety SymptomsImproves (the measure goes down)
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- Grade C
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Studies cited
4 studies from PubMed