Damiana is a Central American shrub traditionally used by the Maya as an aphrodisiac and physical tonic, often brewed as tea. Contains flavonoids (notably apigenin), terpenoids, and volatile oils. Very limited research - a few animal studies suggest mild aphrodisiac effects in fatigued or sluggish animals, possibly due to adaptogenic rather than specific pro-sexual effects. Any anxiolytic effects may be due to apigenin content. No human clinical trials for aphrodisiac claims.
Damiana is a Central American shrub traditionally used by the Maya as an aphrodisiac and physical tonic, often brewed as tea. Contains flavonoids (notably apigenin), terpenoids, and volatile oils.
No specific caution or interaction language was detected in the current summary/outcome notes.
Best grade per condition (each condition may have multiple outcomes)
2 shared conditions · 6 outcomes
Phellodendron amurense is a Traditional Chinese Medicine (TCM) herb used for inflammation, infection, and bone conditions. Contains berberine (same alkaloid as in berberine supplements) and other alkaloids. Often combined with Magnolia officinalis in 'Relora' for stress/cortisol. NO GRADED OUTCOMES for the herb itself. Anti-inflammatory and antimicrobial effects in preclinical research. Limited Western clinical evidence. The berberine content may provide some of the effects attributed to berberine supplements.
2 shared conditions · 5 outcomes
Matured hop extract (MHBA) consists of iso-α-acids from hops (Humulus lupulus) that have undergone oxidation during storage, converting to more complex bitter compounds. Found in aged beer and marketed as a supplement. NO GRADED OUTCOMES - limited research. Proposed benefits include cognitive function, anti-inflammatory effects, and metabolic health. Different from fresh hop extracts used for sleep/relaxation. Research is emerging but insufficient for recommendations.
2 shared conditions · 10 outcomes
Fennel essential oil is extracted from fennel seeds and used in aromatherapy as a 'stimulatory' essential oil. Contains trans-anethole (60-80%), which has estrogenic activity. NO GRADED OUTCOMES - limited clinical evidence. Used traditionally for digestive complaints, respiratory conditions, and lactation support. The estrogenic activity raises safety concerns for hormone-sensitive conditions. May have mild anxiolytic and antispasmodic effects when inhaled. Not recommended for internal use due to potential toxicity. For fennel seed evidence, see the fennel entry.
2 shared conditions · 318 outcomes
Ashwagandha has been called the king of Ayurvedic herbs. It’s best known for reducing stress and anxiety. It may also modestly enhance various aspects of physical performance, increase testosterone levels, and improve reproductive health, but more research is needed to confirm these effects.
1 shared condition · 5 outcomes
ZMA is a patented combination of zinc monomethionine aspartate, magnesium aspartate, and vitamin B6. Marketed for testosterone and athletic performance. REALITY: Independent studies (not funded by patent holder) show NO testosterone or performance benefits in non-deficient individuals. Original testosterone study was funded by patent holder and not replicated. ZMA only benefits those DEFICIENT in zinc or magnesium. Just buy zinc and magnesium separately for less money.
1 shared condition · 25 outcomes
Yohimbine is an alpha-2 adrenergic receptor antagonist from the Pausinystalia yohimbe tree bark. C-grade evidence for fat loss and erectile dysfunction. SIGNIFICANT SAFETY CONCERNS: Causes anxiety, elevated heart rate, and blood pressure increases - contraindicated in cardiovascular conditions, anxiety disorders, and panic disorder. Supplement quality is notoriously poor - actual yohimbine content varies widely from label claims. Effective for fat loss during fasted cardio but side effects limit use.
1 shared condition · 6 outcomes
White Kidney Bean extract (Phase 2) is an alpha-amylase inhibitor that blocks starch digestion. It DOES work but potency is variable and modest - blocks ~25-65% of starch calories in acute studies. Meta-analyses show ~2kg weight loss over 4-12 weeks. Must be taken with starchy meals. Undigested starch goes to colon bacteria (gas, bloating). Better for preventing weight gain than losing existing weight. Works best with high-starch meals.
1 shared condition · 197 outcomes
Whey protein is one of the two high-quality proteins derived from cow’s milk (casein being the other). Its high digestibility, quick absorption, and well-researched benefits for muscle gain and cardiometabolic health make it a popular protein supplement among athletes and older adults.