Protocol · Dermatological/Allergic
Urticaria (Hives) Support Protocol
Vitamin D and Probiotics are the core of this stack, with 3 supporting supplements. Each row gives the amount the protocol lists and the grade our evidence database holds for that supplement in Urticaria (Hives) Support.
We are re-verifying the studies cited on protocol pages; only confirmed citations are shown.
The stack
5 supplements · none graded yet
| Grade | Supplement | Amount listed | Why it’s in the stack | Evidence on file | Shop |
|---|---|---|---|---|---|
| Primary stackThe core of this protocol | |||||
| Vitamin D | Amount listed: 2,000–4,000 IU daily | Deficiency linked to chronic urticaria; supports immune modulation | Not graded yet | ||
| Probiotics | Amount listed: 10–20 billion CFU daily | May help modulate immune response in chronic urticaria | Not graded yet | ||
| Supporting stackListed as additions to the core | |||||
| Vitamin C | Amount listed: 1,000–2,000 mg daily | Natural antihistamine properties; reduces histamine levels | Not graded yet | ||
| Quercetin | Amount listed: 500–1,000 mg daily | Mast cell stabilizer; may reduce histamine release | Not graded yet | ||
| Omega-3 Fatty Acids | Amount listed: 2–3 g EPA+DHA daily | Anti-inflammatory; may help with chronic inflammatory conditions | Not graded yet | ||
Shop the evidence-backed picks
The collection holds the supplements we grade A or B for its theme, in third-party tested products where the catalog has them. It opens in our Fullscript store. You can look through it without signing in; Fullscript asks for a free account to order.
Or shop one supplement
Each opens third-party tested products, matched to the dose above where we can.
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How this protocol works
In plain language
Urticaria (hives) causes itchy, raised, red welts on the skin. It's caused by the release of histamine and other chemicals from cells in the skin.
TYPES:
- Acute urticaria (<6 weeks) - usually allergic or viral
- Chronic urticaria (>6 weeks) - often no identifiable cause
- Physical urticarias (triggered by cold, heat, pressure, sunlight)
- Chronic spontaneous urticaria (most common chronic type)
COMMON TRIGGERS:
- Foods (nuts, eggs, shellfish)
- Medications (NSAIDs, antibiotics)
- Infections
- Insect stings
- Physical triggers (pressure, cold, heat)
- Stress
- Often no identifiable trigger
SYMPTOMS:
- Itchy welts (wheals)
- Red or skin-colored
- Vary in size
- Come and go
- May have angioedema (deeper swelling)
SEEK EMERGENCY CARE IF:
- Difficulty breathing
- Throat tightness
- Swelling of lips/tongue
- Dizziness or fainting
TREATMENT:
- Antihistamines (first-line)
- Avoid triggers if known
- Cool compresses
- For severe: omalizumab, cyclosporine
Vitamin D* deficiency is common in chronic urticaria.
Antihistamines* remain first-line treatment.
Identify and avoid triggers* when possible.
Expected timeline: Acute urticaria usually resolves within days to weeks. Chronic urticaria may last months to years but often eventually resolves.