Protocol · Endocrine Health
General Thyroid Health Support Protocol
Selenium and Iodine are the core of this stack, with 4 supporting supplements. Each row gives the amount the protocol lists and the grade our evidence database holds for that supplement in General Thyroid Health Support.
We are re-verifying the studies cited on protocol pages; only confirmed citations are shown.
The stack
6 supplements · 2 graded
| Grade | Supplement | Amount listed | Why it’s in the stack | Evidence on file | Shop |
|---|---|---|---|---|---|
| Primary stackThe core of this protocol | |||||
| Selenium | Amount listed: 100–200 mcg daily | Essential for thyroid hormone conversion (T4 to T3); antioxidant protection for thyroid | Not graded yet | ||
| Iodine | Amount listed: 150 mcg daily (RDA); avoid excess if autoimmune thyroid disease | Essential component of thyroid hormones; deficiency causes hypothyroidism
| Grade C for Serum T31 study · 32 people | ||
| Supporting stackListed as additions to the core | |||||
| Zinc | Amount listed: 15–30 mg daily | Required for thyroid hormone synthesis; deficiency impairs thyroid function
| Grade C for Free Testosterone10 people | ||
| Vitamin D | Amount listed: 2,000–4,000 IU daily | Deficiency associated with autoimmune thyroid disease; immune modulation | Not graded yet | ||
| Iron | Amount listed: Only if deficient; dose based on level | Required for thyroid peroxidase enzyme; deficiency impairs thyroid function | Not graded yet | ||
| B-Complex Vitamins | Amount listed: B-complex daily | Support overall metabolism; B12 often deficient with thyroid disease | Not graded yet | ||
Shop this protocol
Each opens third-party tested products, matched to the dose above where we can.
- Grade C
- Grade C
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How this protocol works
In plain language
The thyroid gland produces hormones that regulate metabolism, energy, growth, and many body functions. Maintaining thyroid health involves ensuring adequate nutrient intake and avoiding factors that can harm the thyroid.
THYROID HORMONES:
- T4 (thyroxine): Main hormone produced by thyroid
- T3 (triiodothyronine): Active form; converted from T4
- TSH: Brain hormone that stimulates thyroid
COMMON THYROID CONDITIONS:
- Hypothyroidism: Underactive thyroid (fatigue, weight gain, cold intolerance)
- Hyperthyroidism: Overactive thyroid (weight loss, anxiety, rapid heart rate)
- Hashimoto's: Autoimmune hypothyroidism
- Graves': Autoimmune hyperthyroidism
- Nodules: Growths on thyroid
- Goiter: Enlarged thyroid
NUTRIENTS ESSENTIAL FOR THYROID:
- Iodine: Building block of thyroid hormones
- Selenium: Converts T4 to T3; protects thyroid
- Zinc: Required for hormone synthesis
- Iron: Needed for thyroid peroxidase enzyme
- Vitamin D: Immune regulation
IMPORTANT CAUTIONS:
- Excess iodine can WORSEN autoimmune thyroid disease
- Don't take iodine supplements if you have Hashimoto's or Graves' without doctor guidance
- Don't take thyroid supplements (glandulars) without medical supervision
THYROID-DISRUPTING FACTORS:
- Goitrogens in raw cruciferous vegetables (cooking reduces effect)
- Soy (may interfere with thyroid medication absorption)
- Environmental toxins (BPA, perchlorate, fluoride)
- Stress
- Gluten (possible connection with autoimmune thyroid)
Selenium* is especially important - supports conversion and protects the gland.
Iodine* - ensure adequate intake but avoid excess.
Check for deficiencies* in iron, B12, vitamin D.
Expected timeline: Nutrient optimization may improve thyroid function over 2-3 months. Always work with a healthcare provider for thyroid concerns.