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Protocol · Liver/Infectious Disease

Hepatitis C Supportive Care Protocol

TUDCA (Tauroursodeoxycholic Acid) and Milk Thistle (Silymarin) are the core of this stack, with 3 supporting supplements. Each row gives the amount the protocol lists and the grade our evidence database holds for that supplement in Hepatitis C Supportive Care.

We are re-verifying the studies cited on protocol pages; only confirmed citations are shown.

The stack

5 supplements · 1 graded

Amount listed in this protocol; not a recommendation.

Supplements in the Hepatitis C Supportive Care protocol, with the amount the protocol lists, the grade on file and confirmed studies
GradeSupplementAmount listedWhy it’s in the stackEvidence on fileShop
Primary stackThe core of this protocol
TUDCA (Tauroursodeoxycholic Acid)Amount listed: 250–500 mg daily

Bile acid that supports liver cell protection and reduces liver stress

  • Liver Cell Content: improves
  • Liver Enzymes: changes; see studies
Grade C for Liver Cell Content1 study · 5 people
Milk Thistle (Silymarin)Amount listed: 420 mg silymarin daily (divided doses)

Hepatoprotective; antioxidant; may support liver function

Not graded yet
Supporting stackListed as additions to the core
N-Acetyl Cysteine (NAC)Amount listed: 600–1,200 mg daily

Glutathione precursor; antioxidant support for liver

Not graded yet
Vitamin DAmount listed: 2,000–4,000 IU daily

Deficiency common in chronic liver disease; may affect treatment response

Not graded yet
ZincAmount listed: 15–30 mg daily

Often deficient in liver disease; supports immune function

Not graded yet

Shop this protocol

Support alongside medical care. These supplements are not a treatment for Hepatitis C. If you are being treated for it, talk to your clinician before adding one: supplements can interact with medicines.

Each opens third-party tested products, matched to the dose above where we can.

  • Grade C

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How this protocol works

In plain language

Hepatitis C is a viral infection that affects the liver. Thanks to modern direct-acting antiviral (DAA) medications, hepatitis C is now curable in over 95% of cases.

ABOUT HEPATITIS C:

  • Caused by hepatitis C virus (HCV)
  • Spread through blood-to-blood contact
  • Many people have no symptoms for years
  • Can lead to cirrhosis, liver cancer if untreated
  • Now highly curable with medications

SYMPTOMS (when present):

  • Fatigue
  • Abdominal pain
  • Loss of appetite
  • Nausea
  • Dark urine
  • Jaundice (yellow skin/eyes) - late stage

CRITICAL: Hepatitis C is now curable. See a healthcare provider for testing and treatment. This protocol is SUPPORTIVE ONLY.

MEDICAL TREATMENT:

  • Direct-acting antivirals (DAAs): 8-12 weeks of pills
  • Cure rate >95%
  • Examples: sofosbuvir/velpatasvir, glecaprevir/pibrentasvir
  • Minimal side effects compared to old interferon treatments

LIVER HEALTH SUPPORT:

  • Avoid alcohol completely
  • Maintain healthy weight
  • Avoid hepatotoxic medications when possible
  • Get vaccinated for hepatitis A and B
  • Regular monitoring of liver function

WHO SHOULD BE TESTED:

  • Everyone born 1945-1965 (baby boomer generation)
  • Anyone who has injected drugs
  • HIV-positive individuals
  • Blood transfusion recipients before 1992
  • Children of HCV-positive mothers

TUDCA and milk thistle* provide hepatoprotective support.

NAC* supports glutathione and liver detoxification.

Correct deficiencies* in vitamin D and zinc.

Expected timeline: DAA treatment cures most people in 8-12 weeks. Supplements support liver health before, during, and after treatment.

Printed from drgrey.ai/protocols/hepatitis-c. For education only; not medical advice. Talk to a clinician before starting any supplement.