Hair Loss (Alopecia) Support Protocol

Dermatological/Cosmetic HealthModerate Evidence
6
supplements
2
Primary
4
Supporting
0
Grade A
40
Studies

Primary Stack

Core supplements with strongest evidence
2.5-5mg daily

Essential B vitamin for keratin production; deficiency causes hair loss

8 studies400 participants
If deficient: 65-200mg elemental iron daily until replete

Deficiency is common cause of hair loss, especially in women; only supplement if deficient

10 studies500 participants

Supporting Stack

Additional supplements for enhanced results
15-30mg daily

Supports hair follicle health; deficiency linked to hair loss

8 studies400 participants
2000-4000 IU daily

Plays role in hair follicle cycling; deficiency associated with alopecia

↑Hair Regrowth
6 studies300 participants

Provides amino acids for hair keratin; supports hair structure

4 studies200 participants
320mg standardized extract daily

May inhibit 5-alpha reductase; potentially helpful for androgenetic alopecia

↑Hair Regrowth
4 studies150 participants

How This Protocol Works

Simple Explanation

Hair loss (alopecia) can have many causes, from genetics to nutritional deficiencies to medical conditions. Understanding the type is important for treatment.

COMMON TYPES:

•Androgenetic alopecia: Most common; male/female pattern baldness; genetic + hormonal
•Telogen effluvium: Diffuse shedding after stress, illness, pregnancy, diet
•Alopecia areata: Autoimmune; patchy hair loss
•Nutritional deficiency: Iron, zinc, biotin, protein deficiency
•Thyroid disorders: Both hypo and hyperthyroidism
•Medication-induced: Various drugs can cause hair loss

WHEN TO SEE A DOCTOR:

•Sudden or patchy hair loss
•Hair loss with scalp symptoms (itching, scaling)
•Hair loss after starting medication
•Associated symptoms (fatigue, weight changes)
•Scarring hair loss

MEDICAL TREATMENTS:

•Minoxidil (Rogaine): FDA-approved; topical; works for various types
•Finasteride (men): Prescription; blocks DHT
•Spironolactone (women): For hormonal hair loss
•Platelet-rich plasma (PRP): Injections; growing evidence
•Hair transplant: For stable androgenetic alopecia

NUTRITIONAL FACTORS:

•Test for iron, ferritin, zinc, vitamin D, thyroid
•Adequate protein intake essential
•Crash diets can trigger telogen effluvium

* Biotin supports keratin production.

* Check and correct deficiencies in iron, zinc, vitamin D.

* Saw palmetto may help androgenetic alopecia.

Expected timeline: Telogen effluvium resolves in 6-12 months. Nutritional supplementation takes 3-6 months to see improvement. Hair grows ~1 cm/month.

Clinical Perspective

Hair Loss: Most common is androgenetic alopecia (AGA). Telogen effluvium from physiologic stress. Workup: pull test, scalp exam, labs (TSH, ferritin, zinc, vitamin D, CBC, ANA if suspected autoimmune). Biopsy if diagnosis unclear.

Treatment: AGA - minoxidil (both sexes), finasteride (men), spironolactone (women), PRP. Telogen effluvium - address trigger, patience. Nutritional - correct deficiencies (ferritin target >70 for hair). Supplements: biotin if deficient; zinc, iron only if deficient; saw palmetto modest evidence for AGA. Most important: identify and treat underlying cause.

* Biotin (B-grade): Keratin support. Systematic review: (PMID: 28879195). 2.5-5mg daily.

* Iron (B-grade): If deficient. Systematic review: (PMID: 28252380). Target ferritin >70.

* Zinc (B-grade): Hair follicle support. Review: (PMID: 26845419). 15-30mg daily.

* Vitamin D (C-grade): Follicle cycling. Review: (PMID: 28750270). 2000-4000 IU daily.

* Collagen (C-grade): Amino acids. Review: (PMID: 30681787). 5-10g daily.

* Saw Palmetto (C-grade): 5AR inhibition. Review: (PMID: 23298508). 320mg daily.

Assessment targets: Hair density, shedding rate, ferritin, zinc, vitamin D, thyroid function.

Protocol notes: Minoxidil: 5% for men, 2-5% for women; takes 4-6 months; shedding initially normal. Finasteride: men only; 1mg daily; check PSA if prostate screening. Ferritin: aim >70 ng/mL for optimal hair (higher than deficiency cutoff). Biotin: high doses interfere with lab tests (thyroid, cardiac). Telogen effluvium: self-limited but supplement optimization helps recovery. Alopecia areata: intralesional steroids, topical immunotherapy, JAK inhibitors emerging. Scarring alopecia: needs dermatology referral; treatment differs. Diet: adequate protein (0.8-1g/kg); avoid crash diets. PRP: monthly x 3, then maintenance; modest evidence.