Gastritis Support Protocol

GastrointestinalModerate Evidence

supplements

Primary

Supporting

Grade A

Studies

Primary Stack

Core supplements with strongest evidence

ProbioticsB

10-20 billion CFU daily (Lactobacillus and Bifidobacterium strains)

May help with H. pylori eradication when combined with antibiotics

15 studies1,000 participants

Supporting Studies (1)

PMID: 24045160 - Probiotics for H. pylori: meta-analysis (2013)

Zinc-L-CarnosineB

75-150mg twice daily

Supports gastric mucosal healing; studied for gastritis and ulcers

8 studies400 participants

Supporting Studies (1)

PMID: 17308970 - Zinc-carnosine for gastric mucosal disorders: review (2007)

Supporting Stack

Additional supplements for enhanced results

DGL (Deglycyrrhizinated Licorice)C

380-760mg before meals

Supports mucosal protection without mineralocorticoid effects

6 studies300 participants

Supporting Studies (1)

PMID: 22747745 - DGL for gastric disorders: review (2012)

Vitamin B12B

1000mcg daily if deficient

Atrophic gastritis impairs B12 absorption; monitor and supplement if needed

6 studies300 participants

Supporting Studies (1)

PMID: 22566526 - B12 deficiency in gastritis: review (2012)

Mastic GumC

500-1000mg daily

Traditional remedy with some anti-H. pylori activity

5 studies200 participants

Supporting Studies (1)

PMID: 20625626 - Mastic gum for H. pylori: systematic review (2010)

How This Protocol Works

Simple Explanation

Gastritis is inflammation of the stomach lining. It can be acute (sudden onset) or chronic (develops gradually over time).

TYPES:

•Acute gastritis (sudden inflammation)

•Chronic gastritis (develops over time)

•H. pylori gastritis (bacterial infection - most common cause worldwide)

•Autoimmune gastritis (antibodies attack stomach cells)

•Erosive gastritis (from NSAIDs, alcohol)

COMMON CAUSES:

•H. pylori bacterial infection

•NSAIDs (aspirin, ibuprofen)

•Excessive alcohol

•Stress (severe illness, burns, surgery)

•Autoimmune conditions

•Bile reflux

SYMPTOMS:

•Upper abdominal pain or discomfort

•Nausea, vomiting

•Feeling of fullness after eating

•Bloating

•Loss of appetite

•Indigestion

MEDICAL TREATMENT:

•H. pylori: Triple or quadruple antibiotic therapy

•PPIs or H2 blockers to reduce acid

•Stop NSAIDs if contributing

•Limit alcohol

•Treat underlying causes

WHEN TO SEE A DOCTOR:

•Blood in vomit or stool

•Severe abdominal pain

•Unexplained weight loss

•Symptoms lasting more than a week

* Probiotics may help H. pylori treatment.

* Zinc-carnosine supports mucosal healing.

* Address underlying cause is essential.

Expected timeline: Acute gastritis often improves within days to weeks. Chronic gastritis takes longer. H. pylori eradication requires 10-14 day antibiotic course.

Clinical Perspective

Gastritis: Mucosal inflammation. H. pylori most common cause globally. Atrophic gastritis: loss of glandular cells; associated with B12 deficiency, increased gastric cancer risk. Autoimmune: parietal cell antibodies, intrinsic factor deficiency.

Treatment: H. pylori: triple therapy (PPI + clarithromycin + amoxicillin) or quadruple therapy. Probiotics as adjunct may improve eradication rates and reduce antibiotic side effects. Zinc-carnosine studied in Japan for mucosal protection. DGL traditional but limited evidence. Atrophic gastritis: monitor B12, screen for gastric cancer. Address underlying cause (NSAIDs, alcohol, H. pylori).

* Probiotics (B-grade): H. pylori adjunct. Meta-analysis: (PMID: 24045160). 10-20B CFU daily.

* Zinc-Carnosine (B-grade): Mucosal healing. Review: (PMID: 17308970). 75-150mg BID.

* DGL (C-grade): Mucosal protection. Review: (PMID: 22747745). 380-760mg before meals.

* Vitamin B12 (B-grade): Atrophic gastritis. Review: (PMID: 22566526). 1000mcg daily if deficient.

* Mastic Gum (C-grade): Anti-H. pylori. Systematic review: (PMID: 20625626). 500-1000mg daily.

Protocol notes: H. pylori testing: urea breath test, stool antigen, or biopsy. Eradication: confirm with post-treatment testing. Resistance: clarithromycin resistance increasing; culture/sensitivity if failure. PPIs: cornerstone of acid suppression; duration varies. NSAIDs: if must use, add PPI; consider COX-2 selective. Atrophic gastritis: B12 monitoring; endoscopic surveillance for dysplasia/cancer. Alcohol: abstinence or reduction. Diet: no specific diet proven; avoid individual trigger foods.

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