Protocol · Mental Health & Mood
Adjustment Disorder Supportive Care Protocol
Ashwagandha and Lavender Oil (Silexan) are the core of this stack, with 7 supporting supplements. Each row gives the amount the protocol lists and the grade our evidence database holds for that supplement in Adjustment Disorder Supportive Care.
We are re-verifying the studies cited on protocol pages; only confirmed citations are shown.
The stack
9 supplements · none graded yet
| Grade | Supplement | Amount listed | Why it’s in the stack | Evidence on file | Shop |
|---|---|---|---|---|---|
| Primary stackThe core of this protocol | |||||
| Ashwagandha | Amount listed: 300–600 mg standardized extract (KSM-66 or Sensoril) daily | Adaptogen that reduces cortisol and stress response; helps with anxiety and stress-related symptoms | Not graded yet | ||
| Lavender Oil (Silexan) | Amount listed: 80–160 mg Silexan (standardized lavender oil) daily | Anxiolytic effects without sedation; reduces anxiety symptoms comparable to low-dose benzodiazepines | Not graded yet | ||
| Supporting stackListed as additions to the core | |||||
| Magnesium | Amount listed: 300–400 mg daily (glycinate for calming effects) | Calming effect on nervous system; deficiency associated with stress and anxiety symptoms | Not graded yet | ||
| L-Theanine | Amount listed: 100–200 mg daily or as needed | Promotes calm and focus without sedation; increases alpha brain waves | Not graded yet | ||
| Rhodiola Rosea | Amount listed: 200–600 mg standardized extract daily | Adaptogen that reduces fatigue and improves stress resilience | Not graded yet | ||
| Ginkgo Biloba | Amount listed: 120–240 mg standardized extract daily | May improve cognitive function and reduce anxiety symptoms
| Not graded yet | ||
| Omega-3 Fatty Acids | Amount listed: 2–3 g EPA+DHA daily (higher EPA for mood) | Anti-inflammatory effects on brain; may improve mood and reduce anxiety | Not graded yet | ||
| Vitamin D | Amount listed: 2,000–4,000 IU daily (target 40–60 ng/mL) | Deficiency associated with mood disorders; supports overall mental health | Not graded yet | ||
| B Vitamins | Amount listed: B-complex with adequate B6, B12, and folate daily | Support neurotransmitter synthesis and stress response; may reduce anxiety symptoms | Not graded yet | ||
Shop the evidence-backed picks
The collection holds the supplements we grade A or B for its theme, in third-party tested products where the catalog has them. It opens in our Fullscript store. You can look through it without signing in; Fullscript asks for a free account to order.
Or shop one supplement
Each opens third-party tested products, matched to the dose above where we can.
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How this protocol works
In plain language
Adjustment disorder is a stress-related condition that develops when someone has significant difficulty coping with a major life stressor. This could be a relationship breakup, job loss, illness, moving, or any significant change. Unlike normal stress reactions, adjustment disorder symptoms are more severe than expected and interfere with daily functioning. Symptoms can include sadness, hopelessness, anxiety, difficulty concentrating, sleep problems, and physical complaints. By definition, the condition develops within 3 months of the stressor and doesn't last more than 6 months after the stressor ends.
CRITICAL: Adjustment disorder can progress to major depression or anxiety disorder if not addressed. Professional help - particularly psychotherapy - is the primary treatment. Cognitive Behavioral Therapy (CBT) and supportive therapy are very effective. If you have thoughts of self-harm or suicide, seek immediate help. These supplements may help with stress management and mood support but should complement, not replace, professional mental health care.
Ashwagandha* is an adaptogen that helps the body cope with stress. Clinical trials show it significantly reduces cortisol levels and anxiety symptoms. It's particularly helpful for stress-related conditions.
Lavender Oil (Silexan)* is a standardized lavender extract with proven anxiolytic effects. Unlike benzodiazepines, it doesn't cause sedation or dependence.
Magnesium* has a calming effect on the nervous system. Stress depletes magnesium, and deficiency can worsen anxiety symptoms. Glycinate is the preferred form for nervous system support.
L-Theanine* is an amino acid from green tea that promotes calm without sedation. It increases relaxing alpha brain waves and can be taken as needed for acute stress.
Rhodiola Rosea* is an adaptogen that helps with stress-related fatigue and improves overall resilience to stress.
Ginkgo Biloba* may improve cognitive function affected by stress and has some anxiolytic effects.
Omega-3 Fatty Acids* have anti-inflammatory effects on the brain and may improve both mood and anxiety symptoms.
Vitamin D* deficiency is associated with mood disorders. Maintaining adequate levels supports overall mental health.
B Vitamins* support neurotransmitter production and the body's stress response system.
Expected timeline: Ashwagandha and lavender may show effects within 2-4 weeks. L-theanine works acutely. Adaptogens generally need 4-8 weeks for full effects. Adjustment disorder typically resolves within 6 months once the stressor ends, especially with proper support.