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Dr. Grey AI

Condition

Primary Ovarian Insufficiency

Primary ovarian insufficiency is a condition in which the ovaries stop working normally before age 40, so periods become irregular, estrogen runs low, and getting pregnant is often harder. Among supplements, vitamin D and calcium are the ones most often discussed, mainly for bone health, but little research on them in this condition has been reviewed here so far. Because low estrogen speeds bone loss, that link makes sense, yet it isn't a finding from trials in women with this condition.

Supplements studied
0
Graded outcomes
0
People studied
401
No graded evidence yetWe haven’t found supplement studies for Primary Ovarian Insufficiency that meet the bar for a grade.

The Primary Ovarian Insufficiency Support protocol

2 primary supplements · 4 supporting supplements

  • Vitamin D2,000–4,000 IU daily (titrate to levels)
  • Calcium1,000–1,200 mg daily (diet + supplement)

See the full protocol

Shop the evidence-backed picks

Support alongside medical care. These supplements are not a treatment for Primary Ovarian Insufficiency. If you are being treated for it, talk to your clinician before adding one: supplements can interact with medicines.

Fullscript collectionWomen's health: evidence-graded picksOpen on Fullscript

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