Raspberry ketone is an aromatic compound giving raspberries their scent. MASSIVELY OVERHYPED based on Dr. Oz promotion and zero human evidence. The ONLY positive data is from rat studies using doses 100-200x higher than supplements provide. Structurally similar to synephrine/capsaicin. NO human clinical trials showing fat loss. Supplements provide ~100-200mg while effective rat doses translate to 1000-6000mg in humans. Classic example of marketing exceeding science.
Raspberry ketone is an aromatic compound giving raspberries their scent. MASSIVELY OVERHYPED based on Dr.
No specific caution or interaction language was detected in the current summary/outcome notes.
Best grade per condition (each condition may have multiple outcomes)
1 shared condition · 5 outcomes
ZMA is a patented combination of zinc monomethionine aspartate, magnesium aspartate, and vitamin B6. Marketed for testosterone and athletic performance. REALITY: Independent studies (not funded by patent holder) show NO testosterone or performance benefits in non-deficient individuals. Original testosterone study was funded by patent holder and not replicated. ZMA only benefits those DEFICIENT in zinc or magnesium. Just buy zinc and magnesium separately for less money.
1 shared condition · 25 outcomes
Yohimbine is an alpha-2 adrenergic receptor antagonist from the Pausinystalia yohimbe tree bark. C-grade evidence for fat loss and erectile dysfunction. SIGNIFICANT SAFETY CONCERNS: Causes anxiety, elevated heart rate, and blood pressure increases - contraindicated in cardiovascular conditions, anxiety disorders, and panic disorder. Supplement quality is notoriously poor - actual yohimbine content varies widely from label claims. Effective for fat loss during fasted cardio but side effects limit use.
1 shared condition · 6 outcomes
White Kidney Bean extract (Phase 2) is an alpha-amylase inhibitor that blocks starch digestion. It DOES work but potency is variable and modest - blocks ~25-65% of starch calories in acute studies. Meta-analyses show ~2kg weight loss over 4-12 weeks. Must be taken with starchy meals. Undigested starch goes to colon bacteria (gas, bloating). Better for preventing weight gain than losing existing weight. Works best with high-starch meals.
1 shared condition · 197 outcomes
Whey protein is one of the two high-quality proteins derived from cow’s milk (casein being the other). Its high digestibility, quick absorption, and well-researched benefits for muscle gain and cardiometabolic health make it a popular protein supplement among athletes and older adults.
1 shared condition · 262 outcomes
Vitamin C, or ascorbic acid, is an essential vitamin and a very popular supplement due to its antioxidant properties, safety profile, and low price. Many people supplement with vitamin C because it is believed to reduce symptoms of the common cold.
1 shared condition · 7 outcomes
Valine is one of three branched-chain amino acids (BCAAs), along with leucine and isoleucine. It's essential (must come from diet). NO GRADED OUTCOMES for isolated valine. Least studied and likely least important of the BCAAs for muscle building. Generally supplemented as part of BCAA mixture rather than alone. No unique proven benefits compared to other BCAAs. Safe as an amino acid. Adequate protein intake typically provides sufficient valine.
1 shared condition · 100 outcomes
Tribulus terrestris is a plant whose root and fruits are used in Ayurvedic medicine for male virility and general vitality, respectively. It is also used in Traditional Chinese Medicine. It appears to reduce symptoms of sexual dysfunction (but not improve testosterone levels) in men and women and might improve metabolic health as well.
1 shared condition · 5 outcomes
Thai ginseng (Kaempferia parviflora) is NOT related to true ginseng (Panax). It's a rhizome from the ginger family used in Thai traditional medicine primarily for male sexual function. Contains polymethoxyflavones. Some research supports effects on erectile function and physical performance. NO GRADED OUTCOMES. Also researched for anti-inflammatory and metabolic effects. Generally safe as a traditional food/medicine.