| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Fat Mass In rodent models, raspberry ketone at very high doses (0.5-2 g/kg) reduced fat accumulation in rats fed high-fat diets. No human clinical trials exist, and typical supplement doses (100-200 mg) are orders of magnitude below the effective animal doses (human equivalent 1,000-6,000 mg), making translation to humans highly uncertain. | Improves (the measure goes down) | Small effect |
Supplement
Raspberry ketone is the aroma compound that gives red raspberries their scent, and in lab work it appears to influence how fat cells handle stored fat. People mostly look at it for body fat, but the evidence is very limited: rats fed high-fat diets gained less fat, and isolated fat cells released more adiponectin. No human trials exist, so it is unclear whether any of this carries over to people.
- Updated
- How we grade
- Best evidence
- Grade D
- Conditions studied
- 1
- Outcomes
- 2
- Graded outcomes
- 0002
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
General
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Adiponectin In vitro studies on isolated adipocytes showed raspberry ketone increased adiponectin secretion via proposed HSL (hormone-sensitive lipase) activation. These findings have not been replicated in any human study, and the concentrations used in cell culture may not be achievable with oral supplementation at marketed doses. | Improves (the measure goes up) | Small effect |
Key findings
- Fat MassImproves (the measure goes down)
- AdiponectinImproves (the measure goes up)
Shop Raspberry Ketone
Third-party tested Raspberry Ketone products. The evidence above is limited, so read it before you buy.
- Grade D
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