HPV (Human Papillomavirus) Support Protocol
Primary Stack
Core supplements with strongest evidenceMushroom extract that may support immune clearance of HPV
Supporting Studies (1)
May support estrogen metabolism and cervical cell health
Supporting Studies (1)
Supporting Stack
Additional supplements for enhanced resultsSupports immune function; deficiency associated with persistent HPV
Supporting Studies (1)
Deficiency associated with increased cervical dysplasia risk
Supporting Studies (1)
Antioxidant immune support
Supporting Studies (1)
How This Protocol Works
Simple Explanation
HPV (Human Papillomavirus) is the most common sexually transmitted infection. Most infections clear on their own, but persistent infection with high-risk types can lead to cervical and other cancers.
KEY FACTS:
CRITICAL: HPV-related conditions require medical monitoring. This protocol is SUPPORTIVE ONLY.
PREVENTION:
MEDICAL MANAGEMENT:
* AHCC has preliminary evidence for immune support.
* DIM/I3C may support cervical cell health.
* Immune support with vitamins C, D, and folate.
Expected timeline: Most HPV infections clear within 1-2 years. Supplements may support immune clearance but don't replace medical monitoring.
Clinical Perspective
HPV: Most common STI. High-risk types (16, 18) cause ~70% cervical cancers. Most infections clear spontaneously; persistent infection leads to dysplasia/cancer. Screening: Pap smear + HPV co-testing. Vaccination: 9-valent covers most oncogenic types.
Management: Dysplasia requires colposcopy, biopsy, possible LEEP. Supplements: AHCC has pilot data for HPV clearance; DIM/I3C studied for cervical dysplasia with mixed results. Folate deficiency associated with increased risk. Supplements supportive - don't replace vaccination, screening, or treatment of dysplasia.
* AHCC (C-grade): Immune support. Pilot study: (PMID: 25182478). 3g daily x 6 months.
* DIM/I3C (C-grade): Estrogen/cell metabolism. Clinical trial: (PMID: 10912901). 200-400mg daily.
* Vitamin D (C-grade): Immune function. Systematic review: (PMID: 28750270). 2000-4000 IU daily.
* Folate (C-grade): Cell health. Meta-analysis: (PMID: 27450775). 400-800mcg daily.
* Vitamin C (C-grade): Immune support. Review: (PMID: 23440782). 500-1000mg daily.
Protocol notes: Vaccination: most important prevention; catch-up vaccination recommended up to age 45. Screening: Pap + HPV co-testing; screening guidelines vary by age. LEEP: loop electrosurgical excision procedure for CIN2+. Smoking: increases persistence and progression - cessation important. Immune status: immunocompromised have higher persistence rates.