Condition
Diffuse Esophageal Spasm
Diffuse esophageal spasm is a condition in which the esophagus squeezes in an uncoordinated way instead of a smooth wave that pushes food down, causing chest pain and trouble swallowing. Peppermint oil, a smooth muscle relaxer, is the main supplement people look at, but little research on it has been reviewed here so far. Magnesium, ginger and melatonin come up too, with support mostly from how they act in the body.
- Supplements studied
- 1
- Graded outcomes
- 0
- Trials
- 1
- People studied
- 8
Evidence by supplement
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Diffuse Esophageal Spasm Symptoms | Improves (the measure goes down) | 1 study | 8 people | |||
Studies that measured diffuse esophageal spasm symptoms | ||||||
The Diffuse Esophageal Spasm Support protocol
1 primary supplement · 3 supporting supplements
- Peppermint Oil0.2–0.4 ml enteric-coated capsule before meals
Shop the evidence-backed picks
Support alongside medical care. These supplements are not a treatment for Diffuse Esophageal Spasm. If you are being treated for it, talk to your clinician before adding one: supplements can interact with medicines.
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Studies cited
19 studies from PubMed
- Modulation of cognitive performance and mood by aromas of peppermint and ylang-ylang
- Examination of the effectiveness of peppermint aromatherapy on nausea in women post C-section
- Peppermint oil: a treatment for postoperative nausea
- An investigation into the use of aromatherapy in intrapartum midwifery practice
- A randomized trial of peppermint gel, lanolin ointment, and placebo gel to prevent nipple crack in primiparous breastfeeding women
- Aromatherapy with peppermint, isopropyl alcohol, or placebo is equally effective in relieving postoperative nausea
- Early effects of peppermint oil on gastric emptying: a crossover study using a continuous real-time 13C breath test (BreathID system)
- The effect of enteric-coated, delayed-release peppermint oil on irritable bowel syndrome
- Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children
- Treating irritable bowel syndrome with peppermint oil
- Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial
- Treatment of irritable bowel syndrome with peppermint oil. A double-blind study with a placebo
- Peppermint oil (Mintoil) in the treatment of irritable bowel syndrome: a prospective double blind placebo-controlled randomized trial
- Effectiveness of Oleum menthae piperitae and paracetamol in therapy of headache of the tension type
- Effect of peppermint and eucalyptus oil preparations on neurophysiological and experimental algesimetric headache parameters
- Peppermint oil improves the manometric findings in diffuse esophageal spasm
- Premedication with peppermint oil capsules in colonoscopy: a double blind placebo-controlled randomized trial study
- Efficacy of Peppermint oil in diarrhea predominant IBS - a double blind randomized placebo - controlled study
- Effect of peppermint water on prevention of nipple cracks in lactating primiparous women: a randomized controlled trial