Biliary Dyskinesia
A functional gallbladder disorder characterized by biliary-type pain without gallstones, diagnosed by reduced gallbladder ejection fraction (<35-40%) on cholecystokinin-stimulated cholescintigraphy. May benefit from cholecystectomy.
Quick Answer
What it is
A functional gallbladder disorder characterized by biliary-type pain without gallstones, diagnosed by reduced gallbladder ejection fraction (<35-40%) on cholecystokinin-stimulated cholescintigraphy. May benefit from cholecystectomy.
Key findings
- Grade A: Gallbladder Ejection Fraction (Sincalide (Kinevac))
- Grade A: Gallbladder Contraction (Sincalide (Kinevac))
- Grade B: Surgical Outcome Prediction (Sincalide (Kinevac))
Safety
No specific caution or interaction language was detected in the current summary/outcome notes.
ℹ️ Quick Facts
Quick Facts: Biliary Dyskinesia
- Supplements Studied:1
1 supps · 3 outcomes
Detailed Outcomes
A
Gallbladder Ejection Fraction
Standard 60-min sincalide infusion establishes GBEF normal values. Lower limit of normal: 38% at 1% CI. GBEF <35-40% indicates gallbladder dysfunction. Coefficient of variation 19% for 60-min protocol.
large↑Improves
A
Gallbladder Contraction
Reduces gallbladder radiographic size by ≥40% in normal patients. Enables visualization of gallbladder function via cholescintigraphy. Gold standard for acalculous cholecystitis diagnosis.
large↑Improves
B
Surgical Outcome Prediction
81.4% complete symptom resolution after cholecystectomy in low GBEF patients. Systematic review of 1,710 patients. GBEF alone may not reliably predict outcomes; other factors contribute.
moderate↑Improves